FPL 55712 (sodium salt) |
| Catalog No.GC49696 |
A leukotriene receptor antagonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 40786-08-1
Sample solution is provided at 25 µL, 10mM.
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FPL 55712 (sodium salt) is a leukotriene (LT) receptor antagonist.1 It inhibits the binding of LTD4 to guinea pig lung homogenates (IC50 = 4 µM) and reduces LTD4-induced contraction of isolated guinea pig tracheal smooth muscle (pA2 = 1 µM). FPL 55712 (sodium salt) inhibits bronchoconstriction induced by LTD4, LTC4 , or LTE4 in guinea pigs (ID50s = 2, 6, and 1 mg/kg, respectively).
1.Cohen, N., Weber, G., Banner, B.L., et al.3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonistsJ. Med. Chem.32(8)1842-1860(1989)
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