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FTT5

Catalog No.GC65357 Copy One-Click Copy Product Info

FTT5 est un composé de type lipidique pour la délivrance efficace d'ARNm longs in vivo.

Products are for research use only. Not for human use. We do not sell to patients.

FTT5 Chemical Structure

Cas No.: 2328129-27-5

Taille Prix Stock Qté
1mg
190,00 $US
En stock

Tel:(909) 407-4943 Email: sales@glpbio.com


Avis des clients

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of FTT5

FTT5 is a lipid-like compound for efficient delivery of long mRNAs in vivo.

[1]. Zhang X, Zhao W, Nguyen GN, et al. Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing. Sci Adv. 2020;6(34):eabc2315.

Chemical Properties of FTT5

Cas No. 2328129-27-5 SDF
Formula C120H222N6O15 M.Wt 1989.08
Solubility DMSO : 50 mg/mL (25.14 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of FTT5

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 502.7 μL 2.5137 mL 5.0274 mL
5 mM 100.5 μL 502.7 μL 1.0055 mL
10 mM 50.3 μL 251.4 μL 502.7 μL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

Calculate

In vivo Formulation Calculator (Clear solution) of FTT5

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Avis

Review for FTT5

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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