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Ac-Thr-Ile-Nle-psi(CH₂NH)Nle-Gln-Arg-NH₂

Catalog No.GA20657 Copy One-Click Copy Product Info

The sequence of the HIV-1 protease inhibitor Ac-Thr-IIe-Nle-psi[CH2-NH]Nle-Gln-Arg-amide is derived from a known cleavage site of the viral gag-pol poly-protein. Electron density studies showed that this inhibitor binds to the active site of the HIV-1 protease.

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Ac-Thr-Ile-Nle-psi(CH₂NH)Nle-Gln-Arg-NH₂ Chemical Structure

Cas No.: 128657-47-6

Taille Prix Stock Qté
0.5mg
543,00 $US
En stock
1mg
902,00 $US
En stock

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Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Ac-Thr-Ile-Nle-psi(CH₂NH)Nle-Gln-Arg-NH₂

The sequence of the HIV-1 protease inhibitor Ac-Thr-IIe-Nle-psi[CH2-NH]Nle-Gln-Arg-amide is derived from a known cleavage site of the viral gag-pol poly-protein. Electron density studies showed that this inhibitor binds to the active site of the HIV-1

Chemical Properties of Ac-Thr-Ile-Nle-psi(CH₂NH)Nle-Gln-Arg-NH₂

Cas No. 128657-47-6 SDF
Formula C35H67N11O8 M.Wt 769.99
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Ac-Thr-Ile-Nle-psi(CH₂NH)Nle-Gln-Arg-NH₂

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.2987 mL 6.4936 mL 12.9872 mL
5 mM 259.7 μL 1.2987 mL 2.5974 mL
10 mM 129.9 μL 649.4 μL 1.2987 mL
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In vivo Formulation Calculator (Clear solution) of Ac-Thr-Ile-Nle-psi(CH₂NH)Nle-Gln-Arg-NH₂

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for Ac-Thr-Ile-Nle-psi(CH₂NH)Nle-Gln-Arg-NH₂

Average Rating: 5 ★★★★★ (Based on Reviews and 20 reference(s) in Google Scholar.)

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