Tertiapin |
| Catalog No.GA23602 |
Tertiapin (TPN), a potent inhibitor of the inward-rectifier K? channels, blocked a G-protein-gated channel (GIRK1/4) and the ROMK1 channel with nanomolar affinities, however a closely related channel, IRK1, was insensitive to tertiapin. Thus, tertiapin will be a powerful ligand for purifying functional channels as well as for screening pharmaceutical agents against these channels.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 58694-52-3
Sample solution is provided at 25 µL, 10mM.
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Tertiapin (TPN), a potent inhibitor of the inward-rectifier K channels, blocked a G-protein-gated channel (GIRK1/4) and the ROMK1 channel with nanomolar affinities, however a closely related channel, IRK1, was insensitive to tertiapin. Thus, tertiapin
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