diABZI STING agonist-1 |
| Catalog No.GC35853 |
diABZI STING agonist-1 est un stimulateur sélectif des récepteurs des gènes de l'interféron (STING), avec des CE50 de 130, 186 nM pour l'homme et la souris, respectivement.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2138299-33-7
Sample solution is provided at 25 µL, 10mM.
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diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist. STING[1].
diABZI STING agonist-1 activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting-/- mice, confirming that diABZI STING agonist-1 induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].
[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.
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