Idalopirdine (Synonyms: Lu AE58054) |
| Catalog No.GC36291 |
L'idalopirdine (Lu AE58054) est un antagoniste puissant et sélectif des récepteurs 5-HT6 avec un Ki de 0,83 nM.
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Cas No.: 467459-31-0
Sample solution is provided at 25 µL, 10mM.
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Idalopirdine (Lu AE58054) is a potent and selective 5-HT6 receptor antagonist with a Ki of 0.83 nM.
[1]. Arnt J, Bang-Andersen B, Grayson B, Lu AE58054, a 5-HT6 antagonist, reverses cognitive impairment induced by subchronic phencyclidine in a novel object recognition test in rats. Int J Neuropsychopharmacol. 2010 Sep;13(8):1021-33. [2]. Witten L, Bang-Andersen B, Nielsen SM, Characterization of [•H]Lu AE60157 ([•H]8-(4-methylpiperazin-1-yl)-3-phenylsulfonylquinoline) binding to 5-hydroxytryptamine• (5-HT•) receptors in vivo.Eur J Pharmacol. 2012 Feb 15;676(1-3):6-11.
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