N-CBZ-Phe-Arg-AMC (Synonyms: Z-FR-AMC) |
Catalog No.GC36707 |
N-CBZ-Phe-Arg-AMC (Z-FR-AMC) est un substrat de cathepsine utilisé dans l'évaluation de l'activité des enzymes cathepsines lysosomales.
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Cas No.: 65147-22-0
Sample solution is provided at 25 µL, 10mM.
N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes[1][2].
[1]. Xu P, et al. Ascorbic acid modulation of iron homeostasis and lysosomal function in trabecular meshwork cells. J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):246-53. [2]. Porter K,et al. Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. Autophagy. 2013 Apr;9(4):581-94.
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