I-191 |
| Catalog No.GC64979 |
I-191 est un antagoniste puissant et sélectif du récepteur 2 activé par la protéase (PAR2).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1690172-25-8
Sample solution is provided at 25 µL, 10mM.
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I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist[1].
I-191 inhibits cytokine production as well as cytokine-related caspase cleavages via ERK1/2 signaling in HT29 colon cancer cells[1].
[1]. Jiang Y, et al. A Potent Antagonist of Protease-Activated Receptor 2 That Inhibits Multiple Signaling Functions in Human Cancer Cells. J Pharmacol Exp Ther. 2018 Feb;364(2):246-257.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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