(+)-Macrosphelide A |
| Catalog No.GC45266 |
(+) - Le macrophelide A est un antibiotique macrolide.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 172923-77-2
Sample solution is provided at 25 µL, 10mM.
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(+)-Macrosphelide A is a fungal metabolite originally isolated from Microsphaeropsis. It inhibits adhesion of HL-60 human leukemia cells to human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner. It also inhibits the growth of SKOV3 ovarian cancer cells in a concentration-dependent manner. (+)-Macrosphelide A inhibits the growth of Gram-positive bacteria, including B. subtilis, M. luteus, B. thuringiensis, and S. aureus (MICs = 143, 143, 57, and 57 μg/ml, respectively), but not Gram-negative bacteria or fungi.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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