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Noscapine HCl (Synonyms: Narcotine, Opianine)

Catalog No.GC11487

Multi-action opioid alkaloid

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Noscapine HCl Chemical Structure

Cas No.: 912-60-7

Taille Prix Stock Qté
10mM (in 1mL DMSO)
36,00 $US
En stock
1g
248,00 $US
En stock
5g
560,00 $US
En stock
10g
933,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products
Noscapine hydrochloride is the hydrochloride form of Noscapine. Noscapine is an opioid alkaloid with several actions. Antagonist at Bradykinin B Receptor (bradykinin receptors) (pA2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated cAMP increases in CNS tissues. Additionally Noscapine binds to tubulin, arrests cells in mitosis and induces apoptosis. Blocks proliferation of human leukemia and multiple myeloma cells. Furthermore, Noscapine modulates IKK activation, suppressing the NF-κB signaling pathway. Exhibits anti-inflammatory activity. Noscapine hydrochloride is an inhibitor of Tubulin.

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Average Rating: 5 ★★★★★ (Based on Reviews and 10 reference(s) in Google Scholar.)

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