O-Desmethyl Midostaurin-d5 (Synonyms: CGP62221-d5; O-Desmethyl PKC412-d5) |
| Catalog No.GC61148 |
O-Desmethyl PKC412-d5 (CGP62221-d5) est un O-Desmethyl PKC412 marqué au deutérium. La O-desméthyl midostaurine (CGP62221; O-desméthyl PKC412) est le métabolite actif de la midostaurine via le métabolisme des enzymes hépatiques du cytochrome P450.
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Sample solution is provided at 25 µL, 10mM.
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O-Desmethyl PKC412-d5 (CGP62221-d5) is a deuterium labeled O-Desmethyl PKC412. O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin via cytochrome P450 liver enzyme metabolism[1].
[1]. Levis M, et al. Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors. Blood. 2006 Nov 15;108(10):3477-83.
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