Ornidazole (Synonyms: NSC 95075, (±)-Ornidazole, Ro 7-0207) |
| Catalog No.GC10025 |
L'ornidazole (Ro 7-0207) est un dérivé du 5-nitroimidazole aux propriétés antiprotozoaires et antibactériennes contre les bactéries anaérobies.
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Cas No.: 16773-42-5
Sample solution is provided at 25 µL, 10mM.
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Ornidazole(Ro 7-0207) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria. Target: Antibacterial; AntiparasiticOrnidazole is a drug that cures some protozoan infections. Ornidazole 1 g/day is effective for the prevention of recurrence of Crohn's disease after ileocolonic resection [1]. Ornidazole is converted to reduction products that interact with DNA to cause destruction of helical DNA structure and strand leading to a protein synthesis inhibition and cell death in susceptible organisms [2].
References:
[1]. Rutgeerts, P., et al., Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology, 2005. 128(4): p. 856-61.
[2]. Goldstein, E.J., V.L. Sutter, and S.M. Finegold, Comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and SC-28538. Antimicrob Agents Chemother, 1978. 14(4): p. 609-13.
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