Pain Research
Products for Pain Research
- Cat.No. Nom du produit Informations
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GC49097
α-Conotoxin AuIB (trifluoroacetate salt)
GCCSYPPCFATNPDC
A conotoxin and an antagonist of α3β4 subunit-containing nAChRs -
GC41499
α-Phellandrene
p-Mentha-1,5-diene, (±)-α-Phellandrene
α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities. -
GC45234
β-Endorphin (1-27) (human) (trifluoroacetate salt)
β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors).
-
GC49865
γ-D-Glutamylglycine (trifluoroacetate salt)
γ-DGG
An excitatory amino acid antagonist -
GC46288
(±)-Epibatidine (hydrochloride)
CMI 545 dihydrochloride
An agonist of α4β2 subunit-containing nAChRs -
GC49515
(±)-Ibuprofen-d3 (sodium salt)
DL-Ibuprofen-d3
An internal standard for the quantification of (±)-ibuprofen -
GC41685
(±)-WIN 55,212 (mesylate)
(±)-WIN 55,212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki value of 62.3 and 3.3 nM for human recombinant central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively.
-
GC41191
(±)13(14)-EpDPA
(±)13,14-EDP, (±)13,14-EpDPE, (±)13,14-epoxy DPA, (±)13,14-epoxy Docosapentaenoic Acid
(M)13(14)-EpDPA (13,14-EpDPE) est le produit de la réaction de la cytochrome P-450 époxygénase avec l'acide docosahexaénoïque (DHA). -
GC41203
(±)7(8)-EpDPA
(±)7,8-EDP, (±)7,8-EpDPE, (±)7,8-epoxy DPA, (±)7,8-epoxy Docosapentaenoic Acid
Docosahexaenoic acid is the most abundant ω-3 fatty acid in neural tissues, especially in the brain and retina. -
GC18343
(-)-CP 55,940
(-)-CP 55,940 is a potent and non-selective cannabinoid (CB) receptor agonist with Ki values of 0.5 to 5 and 0.69 to 2.8 nM for CB1 and CB2 receptors, respectively.
-
GC40594
(R)-AM1241
(+)AM1241
(R)-AM1241 binds to cannabinoid (CB) receptors and has greater than 100-fold selectivity for the CB2 over the CB1 receptor (Kis = 15 and 5,000 nM, respectively, in a membrane assay using human receptors). -
GC40595
(S)-AM1241
(-)AM1241
(S)-AM1241 binds to cannabinoid (CB) receptors and is selective for the CB2 over the CB1 receptor (Kis = 658 and >10,000 nM, respectively, in a membrane assay using human receptors). -
GC46366
1,2,3,4-Tetrahydro-β-carboline
Tetrahydronorharman, Tetrahydro-β-carboline, THBC, Tryptoline
A serotonin reuptake inhibitor and metabolite of tryptamine -
GC49861
1-Carboxycyclohexaneacetic Acid
Gabapentin Impurity E, Gabapentin Related Compound E, NSC 90823
A potential impurity in commercial preparations of gabapentin -
GC46050
1-Deoxysphingosine (m18:1(4E))
1-deoxySO, 4E-1-Deoxysphingosine (m18:1)
An atypical sphingolipid -
GC18783
13,14-dihydro-15-keto Prostaglandin E1
11α-Hydroxy-9,15-diketoprostanoic Acid, 15-keto-PGE0, 13,14-dihydro-15-keto PGE1, 15-keto-dihydro-PGE1, 15-keto Prostaglandin E0
13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity. -
GC42258
3-Cysteinylacetaminophen (trifluoroacetate salt)
3-(cysteine-S-yl)acetaminophen, APAP-Cys
An acetaminophen-protein adduct -
GC49752
4,5-Desisopropylidene Topiramate
4,5-Desisopropylidene TPM
An inactive metabolite of topiramate -
GC18582
5'-hydroxy Meloxicam
A metabolite of meloxicam
-
GC49119
5-hydroxy Flunixin
A metabolite of flunixin
-
GC42550
5-hydroxy-6-methoxy (S)-Duloxetine
5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine.
-
GC42580
6-hydroxy Chlorzoxazone
NSC 24955
6-hydroxy Chlorzoxazone is a metabolite of chlorzoxazone.
-
GC48880
7-Methoxyflavone
La 7-méthoxyflavone est un composé isolé de Zornia brasiliensis.
-
GC40759
8-methyl Nonanoic Acid
Isocapric Acid
Capsaicin, the chemical that imparts the spicy-hot quality of chili peppers, is produced by the fruits of plants belonging to the Capsicum family.
-
GC42693
Acetaminophen Glucuronide (sodium salt)
4-Acetamidophenol Glucuronide, APAP Glucuronide, 4'-Hydroxyacetanilide Glucuronide, Paracetamol Glucuronide
Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen. -
GC42694
Acetaminophen sulfate (potassium salt)
4-Acetamidophenol sulfate, APAP sulfate, 4'-Hydroxyacetanilide sulfate, Paracetamol sulfate
Acetaminophen sulfate is a metabolite of acetaminophen. -
GC46781
Acetaminophen-d4
4-Acetamidophenol-d4, APAP-d4, 4'-Hydroxyacetanilide-d4
A Certified Reference Material -
GC42704
Acetyl β-Endorphin (human) (trifluoroacetate salt)
N-acetyl β-endorphin
Acetyl β-endorphin is an acetylated derivative of β-endorphin that binds to opioid receptors in rat caudal dorsomedial medulla (Ki = 490 nM) and mouse brain membrane preparations (IC50 = 109 nM). -
GC46789
Acetyl-L-carnitine-d3 (chloride)
ALCAR-d3, L-Acetylcarnitine-d3, C2:0 Carnitine-d3, CAR 2:0-d3, L-Carnitine acetyl ester-d3
An internal standard for the quantification of L-acetylcarnitine -
GC49639
Akuammine
(-)-Akuammine, Vincamajoridine
An indole alkaloid with analgesic activity -
GC46826
Alclofenac
An NSAID
-
GC42809
Angiotensin II (3-8) (human, rat, mouse) (trifluoroacetate salt)
Angiotensin IV (human, rat, mouse)
Angiotensin II (3-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II.
-
GC46856
Angiotensin II (5-8) (human, rat, mouse) (trifluoroacetate salt)
Angiotensin (5-8)
An endogenous angiotensin II fragment
-
GC46858
Anthirine
Antirhine
An alkaloid with analgesic activity -
GC49473
ARA 290 (acetate)
Cibinetide, PHBSP, Pyroglutamate HBSP, Pyroglutamate Helix B Surface Peptide
A derivative of EPO -
GC46877
Arachidonoyl Glycine-d8
NAGlyd8, NArachidonyl Glycined8
An internal standard for the quantification of arachidonoyl glycine -
GC42865
AT-121
L'AT-121 est un agoniste bifonctionnel de la nociception et des récepteurs opioÏdes mu, avec un Kis de 3,67 et 16,49 nM, respectivement.
-
GC42885
AX 048
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes.
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GC52409
BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt)
BAM 8-22, Bovine Adrenal Medulla 8-22
A neuropeptide and MRGPRX1 agonist -
GC52407
BAM-22P (human, mouse, rat, bovine) (trifluoroacetate salt)
Bovine Adrenal Medullary Docosapeptide, YGGFMRRVGRPEWWMDYQKRYG
A neuropeptide -
GC49019
BAN ORL 24 (hydrochloride)
A nociceptin receptor antagonist
-
GC39344
BAY-1797
BAY-1797 est un antagoniste P2X4 puissant, actif par voie orale et sélectif, avec une IC50 de 211 nM contre le P2X4 humain.
-
GC49836
Benoxaprofen
LRCL 3794, NSC 299582
Le bénoxaprofène (LRCL 3794) est un composé anti-inflammatoire et antipyrétique puissant et À longue durée d'action. -
GC49300
BIM-46187 (hydrochloride)
An inhibitor of heterotrimeric G-protein signaling
-
GC52145
Bradykinin (human, mouse, rat, bovine) (acetate)
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH, BK, RPPGFSPFR-OH
-
GC49880
Bradykinin (trifluoroacetate salt)
An endogenous vasodilator
-
GC52424
Bradykinin Fragment (1-5) (trifluoroacetate salt)
Arg-Pro-Pro-Gly-Phe, BK1-5, RPPGF
A metabolite of bradykinin -
GC42990
Bupivacaine
La bupivacaÏne est un inhibiteur des récepteurs NMDA.
-
GC46959
Bupivacaine-d9
La bupivacaÏne-d9 est une bupivacaÏne marquée au deutérium.
-
GC49761
Capsaicin-d3
La capsaÏcine-d3 ((E)-capsaÏcine-d3) est la capsaÏcine marquée au deutérium. La capsaÏcine ((E)-capsaÏcine), un composant actif des piments, est un agoniste du TRPV1. La capsaÏcine a des effets analgésiques, antioxydants, anti-inflammatoires, neuroprotecteurs et anticancéreux.
-
GC49433
Capsiate
Capsiate, en tant qu'analogue de capsaÏcine extrait d'un cultivar non piquant de poivron rouge CH-19, est un agoniste actif par voie orale du TRPV1 .
-
GC43155
CAY10448
Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper.
-
GC43171
CAY10568
Santinamide
Most local anesthetics act by abolishing voltage gated sodium channel currents indiscriminately in all populations of neurons. -
GC49226
CAY10787
Δ3,5-Cholestadien-7-one, CSD, NSC 18180, NSC 134914
An oxysterol and a negative allosteric modulator of GABAA receptors -
GC18695
CB-86
CB-86 is a resorcinol-anandamide hybrid compound that acts as a partial agonist for the central cannabinoid (CB1) receptor and a neutral antagonist for the peripheral cannabinoid (CB2) receptor with Ki values of 5.6 and 7.9 nM, respectively.
-
GC52438
CGRP (8-37) (mouse, rat) (trifluoroacetate salt)
Calcitonin Gene-Related Peptide (8-37), CGRP8-37, VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2
A CGRP receptor antagonist -
GC49191
Chlorzoxazone-d3
An internal standard for the quantification of chlorzoxazone
-
GC18369
Cimicoxib
UR8880
Le cimicoxib (CX) est un inhibiteur puissant et sélectif de la COX-2 (cyclo-oxygénase-2) actif par voie orale. -
GC18728
CJ-13610
CJ-13610, un inhibiteur de 5-LO de type non redox, supprime de manière dose-dépendante la formation de produit 5-LO dans le PMNL stimulé par l'ionophore A23187 en l'absence d'AA exogène avec une IC50 d'environ 70 nM.
-
GC52243
Corynantheidine
(-)-Corynantheidine, 9-demethoxy Mitragynine
An alkaloid with antinociceptive activity -
GC43327
CTAP (trifluoroacetate salt)
CTAP is a water soluble, cyclic octapeptide which acts as a receptor antagonist that is selective for the μ opioid receptor (IC50 = 3.5 nM) over the δ receptor (IC50 = 4,500 nM).
-
GC52077
CTP354
CTP354 est le deutérium marqué L-838417.
-
GC43373
D-Amino Acid Oxidase Inhibitor
DAAO inhibitor
D-Amino acid oxidase inhibitor is an inhibitor of D-amino acid oxidase (DAAO) with IC50 values of 145 and 114 nM in CHO cells expressing human and rat DAAO, respectively. -
GC43383
DBO-83
DBO-83 is an agonist of nicotinic acetylcholine receptors (nAChRs) with antinociceptive and anti-amnesic activities.
-
GC43391
Decanoic Acid (sodium salt)
C10:0, Capric Acid, Decylic Acid
Decanoic acid is a saturated medium-chain fatty acid that contains 10 carbons. -
GC45815
Decanoic Acid-d19
Capric Acid-d19, Decylic Acid-d19
An internal standard for the quantification of decanoic acid -
GC46127
Decanoic Acid-d2
C10:0-d2, Capric Acid-d2, Decylic Acid-d2
An internal standard for the quantification of decanoic acid -
GC45722
Decanoic Acid-d3
Capric Acid-d3, Decylic Acid-d3
An internal standard for the quantification of decanoic acid -
GC49338
Deltorphin II (trifluoroacetate salt)
DADELT II, D-Ala2Deltorphin II, D-Ala2, Glu4Deltorphin II, Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2
A peptide agonist of δ2-opioid receptors -
GC47188
Dermorphin (acetate)
An opioid peptide
-
GC49858
Desipramine-d4 (hydrochloride)
Demethylimipramine-d4, Desimipramine-d4, Desmethylimipramine-d4, DMI-d4
An internal standard for the quantification of desipramine -
GC47212
Diclofenac amide
Diclofenac Lactam, 1-(2,6-Dichlorophenyl)oxindole, NSC 621845
A prodrug form of diclofenac -
GC43446
Diclofenac ethyl ester
An esterified form of diclofenac
-
GC43447
Diclofenac methyl ester
Methanol Diclofenac ester
Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac. -
GC49304
Difelikefalin (trifluoroacetate salt)
CR845, FE 202845
A κ-opioid receptor agonist -
GC49829
DL-threo-β-Hydroxyaspartic Acid
DL-THA, DL-threo-3-Hydroxyaspartic Acid
An EAAT inhibitor -
GC47314
Ethopropazine (hydrochloride)
NSC 64074, NSC 169467
Le chlorhydrate d'éthopropazine (isothazine) est un puissant inhibiteur sélectif de la BChE et un mauvais inhibiteur de l'AChE. -
GC47323
Etofenamate-d4
An internal standard for the quantification of etofenamate
-
GC47336
Fenobam (hydrate)
A noncompetitive antagonist and inverse agonist of mGluR5
-
GC49747
Flunixin-d3
An internal standard for the quantification of flunixin
-
GC45761
Flupirtine-d4 (hydrochloride)
D 9998-d4 hydrochloride
Le chlorhydrate de flupirtine-d4 (D 9998-d4) est la flupirtine marquée au deutérium. -
GC47388
Gabapentin-d4
An internal standard for the quantification of gabapentin
-
GC49154
Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
AR-M1896, Gal(2-11)-NH2, WTLNSAGYLL-NH2
A synthetic peptide fragment of galanin and an agonist of the GAL2 receptor -
GC48326
Galanin (human) (acetate)
GAL (human), Galanin (1-30)
A neuropeptide and GAL receptor agonist -
GC43724
Galanin (rat, mouse) (trifluoroacetate salt)
GAL (rat, mouse)
Galanin is a neuropeptide with diverse biological activities.
-
GC43738
GAT211
GAT211 est un modulateur allostérique positif (PAM) du récepteur cannabinoÏde 1 (CB1R).
-
GC43774
Glycerophospho-N-Arachidonoyl Ethanolamine
Glycerophosphoanandamide, GlycerophosphoArachidonoyl Ethanolamide, GPNArE
N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. -
GC49509
Glycyl-L-Glutamine (hydrate)
Glycylglutamine, Gly-Gln
A dipeptide fragment of β-endorphin -
GC18181
GW 405833
L-768,242
GW 405833 (L768242) est un agoniste puissant et sélectif du récepteur cannabinoïde 2 (CB2) avec une EC50 de 50,7 nM. -
GC49882
Hemokinin 1 (human) (trifluoroacetate salt)
HK-1, TGKASQFFGLM-NH2, Thr-Gly-Lys-Ala-Ser-Gln-Phe-Phe-Gly-Leu-Met-NH2
A peptide agonist of NK1 receptors -
GC48453
Hodgkinsine
(–)-Hodgkinsine
An alkaloid with analgesic activity -
GC48454
Hodgkinsine B
(–)-Hodgkinsine B
An alkaloid with analgesic activity -
GC49559
Hydroxymethyl Tolperisone (hydrochloride)
A metabolite of tolperisone
-
GC43891
IDFP
Isopropyl Dodecylfluorophosphonate
The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). -
GC52154
Inflammasome Inhibitor 4b
-
GC43906
Iperoxo (iodide)
Iperoxo (iodure) est un puissant superagoniste du récepteur muscarinique de l'acétylcholine (mAChR).
-
GC47528
Ketorolac (calcium salt)
Le kétorolac (RS37619) hémicalcium est un anti-inflammatoire non stéroÏdien (AINS), agissant comme un inhibiteur non sélectif de la COX, avec des IC50 de 20 nM pour la COX-1 et de 120 nM pour la COX-2.
-
GC52020
Lamotrigine-d3
LTG-d3
An internal standard for the quantification of lamotrigine -
GC49608
Larixyl Acetate
Larixol Acetate
L'acétate de larixyle est un inhibiteur puissant et sélectif de TRPC6 avec des valeurs IC50 de 0,58 μM et 6,83 μM contre hTRPC6-YFP et hTRPC3-YFP, respectivement. -
GC49720
Leu-Enkephalin (trifluoroacetate salt)
Leucine enkephalin, Leu5enkephalin, Tyr-Gly-Gly-Phe-Leu-OH
A neuropeptide and δ- and µ-opioid receptor agonist