Saccharin sodium hydrate |
Catalog No.GC61258 |
L'hydrate de sodium de saccharine est un édulcorant artificiel non calorique actif par voie orale (NAS).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 82385-42-0
Sample solution is provided at 25 µL, 10mM.
Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties[1].
In vitro, Saccharin sodium hydrate (0.5, 2.5, 5 mM) inhibits bacterial growth in a species-dependent manner[1].
In vivo, Saccharin sodium hydrate (oral; 5 mg/kg; twice a day) intake reduces fecal bacterial load and alters microbiome composition, while the intestinal barrier is not obviously affected in male C57BL/6JRj wild type (wt) mice[1].
[1]. SÜnderhauf A, et al. Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice. Nutrients. 2020 Apr 17;12(4). pii: E1122.
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