Salmeterol (GR33343X) |
| Catalog No.GC30092 |
Le salmétérol (GR33343X) (GR33343X) est un β2 agoniste puissant et sélectif des récepteurs adrénergiques humains.
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Cas No.: 89365-50-4
Sample solution is provided at 25 µL, 10mM.
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Salmeterol is a long-acting beta2-adrenergic receptor (beta 2AR) agonist used clinically to treat asthma.Target: beta2-Adrenergic ReceptorSalmeterol is a long-acting beta2-adrenergic receptor agonist drug that is prescribed for the treatment of asthma and chronic obstructive pulmonary disease (COPD). salmeterol also binds with very high affinity at a second site, termed the "exosite", and that this exosite contributes to the long duration of action of salmeterol [1].
[1]. Rong, Y., et al., Probing the salmeterol binding site on the beta 2-adrenergic receptor using a novel photoaffinity ligand, [(125)I]iodoazidosalmeterol. Biochemistry, 1999. 38(35): p. 11278-86.
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