Sphondin |
| Catalog No.GC60345 |
La sphondine possède un effet inhibiteur sur l'augmentation induite par l'IL-1β du niveau de protéine COX-2 et de la libération de PGE2 dans les cellules A549 .
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Cas No.: 483-66-9
Sample solution is provided at 25 µL, 10mM.
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Sphondin, isolated from Heracleum laciniatum, possesses an inhibitory effect on IL-1β-induced increase in the level of COX-2 protein and PGE2 release in A549 cells[1].
Pretreatment of A549 cells with Sphondin (10-50 μM) concentration-dependently attenuates IL-1β-induced COX-2 protein expression and PGE2 release[1].
[1]. Ling Ling Yang, et al. Effects of Sphondin, Isolated From Heracleum Laciniatum, on IL-1beta-induced cyclooxygenase-2 Expression in Human Pulmonary Epithelial Cells. Life Sci. 2002 Nov 29;72(2):199-213.
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