Tiamulin-d10 (hydrochloride) |
| Catalog No.GC46232 |
A neuropeptide with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1322626-74-3
Sample solution is provided at 25 µL, 10mM.
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Tiamulin-d10 is intended for use as an internal standard for the quantification of tiamulin by GC- or LC-MS. Tiamulin is a pleuromutilin antibiotic.1 It is active against M. gallisepticum, M. synoviae, M. iowae, M. hyopneumoniae, M. hyosynoviae, M. hyorhinis, M. bovis, and M. agalactiae (MICs = 0.0025-0.25 μg/ml). Tiamulin is also active against various Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA).2 Tiamulin binds to the peptidyl transferase in the 50S ribosomal subunit to inhibit protein synthesis. Formulations containing tiamulin have been used in the treatment of veterinary enteric diseases and enzootic pneumonia.
|1. Hannan, P.C.T., Windsor, G.D., de Jong, A., et al. Comparative susceptibilities of various animal-pathogenic mycoplasmas to fluoroquinolones. Antimicrob. Agents Chemother. 41(9), 2037-2040 (1997).|2. Wilson, D.N. The A-Z of bacterial translation inhibitors. Crit. Rev. Biochem. Mol. Biol. 44(6), 393-433 (2009).
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