Accueil>>Uridine triphosphate-15N2 dilithium

Uridine triphosphate-15N2 dilithium (Synonyms: UTP-15N2 dilithium; Uridine 5'-triphosphate-15N2 dilithium)

Catalog No.GC26514 Copy One-Click Copy Product Info

Uridine triphosphate-15N2 (UTP-15N2 dilithium;  Uridine 5 '- triphosphate-15N2) dilithium is a 15N labeled Uridine triphosphate.

Products are for research use only. Not for human use. We do not sell to patients.

Uridine triphosphate-15N2 dilithium Chemical Structure

Taille Prix Stock Qté
1mg (100 mM in 20.08 μL Tris HCl buffer pH=7.5)
207,00 $US
En stock
5mg (100 mM in 100.40 μL Tris HCl buffer pH=7.5)
522,00 $US
En stock

Tel:(909) 407-4943 Email: sales@glpbio.com


Avis des clients

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Uridine triphosphate-15N2 dilithium

Uridine triphosphate-15N2 (UTP-15N2 dilithium;  Uridine 5 '- triphosphate-15N2) dilithium is a 15N labeled Uridine triphosphate. Uridine triphosphate (UTP; Uridine 5 '- triphosphate is a nucleotide that regulates pancreatic endocrine and exocrine functions, proliferation, channels, transporters, and intracellular signaling in both normal and diseased states.
References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[2]. Lamarca A, et al. Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation. PLoS One. 2014 Jun 6;9(6):e98998.
[3]. Choi JH, et al. Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor. Pancreas. 2013 May;42(4):680-6.
[4]. Yitzhaki S, et al. Uridine-5'-triphosphate (UTP) reduces infarct size and improves rat heart function aftermyocardial infarct. Biochem Pharmacol. 2006 Oct 16;72(8):949-55.
[5]. Iwaki Y, et al. Enhancement of antibody production against rabies virus by uridine 5'-triphosphate in mice. Microbes Infect. 2014 Mar;16(3):196-202. 

Chemical Properties of Uridine triphosphate-15N2 dilithium

Cas No. SDF
Synonymes UTP-15N2 dilithium; Uridine 5'-triphosphate-15N2 dilithium
Formula C9H13Li215N2O15P3 M.Wt 497.99
Solubility Storage Solution, -20°C, 2 years
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Uridine triphosphate-15N2 dilithium

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0081 mL 10.0404 mL 20.0807 mL
5 mM 401.6 μL 2.0081 mL 4.0161 mL
10 mM 200.8 μL 1.004 mL 2.0081 mL
  • Molarity Calculator

  • Dilution Calculator

  • Molecular Weight Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

Calculate

In vivo Formulation Calculator (Clear solution) of Uridine triphosphate-15N2 dilithium

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

View current batch:

Avis

Review for Uridine triphosphate-15N2 dilithium

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%