GPCR/G protein
Research Areas
- Neuropeptide FF/AF Receptors(54)
- Neuropeptide S Receptor(3)
- GPBA Receptor(5)
- Trace Amine 1 Receptor(2)
- GPCR protein(1)
- FFAR3(1)
- Formyl Peptide Receptors(11)
- 5-HT Receptor(431)
- Acetylcholine(28)
- Adenosine Deaminase(10)
- Adenosine Receptor(143)
- Adenosine Kinase(5)
- Adiponectin Receptor(3)
- Adrenergic Receptor(450)
- Adrenergic Transporters(5)
- Apelin Receptor(9)
- Angiotensin Receptor(118)
- Bombesin Receptors(26)
- Bradykinin Receptors(30)
- Calcitonin and Related Receptors(10)
- Cannabinoid Receptor(121)
- Calcimimetic Agent(2)
- CaSR(28)
- CCK1 Receptors(7)
- CCK2 Receptors(7)
- CCR(98)
- Chemokine Receptors(23)
- CRF1 Receptors(10)
- CRF2 Receptors(3)
- CXCR(108)
- CysLT1 receptor(1)
- Endothelin Receptor(54)
- EP1 Receptor(2)
- EP4 Receptor(2)
- ERRγ(1)
- ETA Receptors(5)
- ETB Receptors(5)
- Free Fatty Acid Receptors(16)
- Galanin Receptors(11)
- Ghrelin Receptors(11)
- GHSR(20)
- GIP Receptor(5)
- Glucagon Receptor(54)
- Glucocorticoid Receptor(103)
- GLUT1(1)
- Gonadotropin-Releasing Hormone Receptors(3)
- GPCR19(12)
- GPR109A(4)
- GPR119(11)
- GPR120(9)
- GPR35(10)
- GPR44(1)
- GPR55(11)
- Hydroxycarboxylic Acid Receptors(5)
- Leukotriene Receptor(57)
- LPA Receptor(12)
- LPL Receptor(64)
- LTD4 Receptor(1)
- mGluR (126)
- Melanin-concentrating Hormone Receptors(7)
- Melanocortin (MC) Receptors(62)
- Melatonin Receptors(23)
- Motilin Receptor(7)
- MT Receptor(1)
- Non-selective CRF(7)
- Neurotensin Receptors(26)
- NK2 Receptors(7)
- NK3 Receptor(5)
- NOP Receptor(20)
- NPY Receptors(26)
- Orexin(3)
- Orphan 7-TM Receptors(6)
- OX Receptor(58)
- Oxytocin Receptors(22)
- P2Y Receptor(66)
- PACAP Receptors(7)
- PAF Receptors(7)
- Peptide Receptors(14)
- PGD2 Receptor(1)
- Prostaglandin Receptor(179)
- Prostanoid Receptors(25)
- Protease-Activated Receptors(9)
- RGS(2)
- S1P receptor(8)
- Secretin Receptors(1)
- Sensory Neuron-Specific Receptors(1)
- Somatostatin Receptor(47)
- Sigma Receptor(62)
- Vasopressin Receptor(34)
- 17,20-lyase(4)
- Ras(180)
- Urotensin-II Receptor(10)
- VIP Receptors(6)
- EBI2/GPR183(7)
- TSH Receptor(12)
- NK Receptor(1)
- GPR81(1)
- C3aR(1)
- CysLT2 receptor(1)
- S1P receptor inhibitor(22)
- CCKB(1)
- FFAR1 (GPR40)(20)
- GPR84(11)
- Neuromedin U Receptors(2)
- Kisspeptin Receptor(8)
- CRFR(27)
- RGS Protein(5)
- Urotensin Receptor(7)
- Cholecystokinin Receptor(29)
- GPR139(4)
- mAChR(200)
- MCHR1 (GPR24)(17)
- Neurokinin Receptor(78)
- cGMP(27)
- GRK(5)
- GPR88(3)
- Amylin Receptor(9)
- Arrestin(10)
- Mas-related G-protein-coupled Receptor (MRGPR)(10)
- GCGR(13)
- GLP Receptor(27)
- Succinate Receptor 1(1)
- PTHR(3)
- Protease Activated Receptor (PAR)(6)
- Free Fatty Acid Receptor(5)
- Formyl Peptide Receptor (FPR)(7)
- Hydroxycarboxylic Acid Receptor (HCAR)(2)
- RXFP Receptor(3)
- Adhesion G Protein-coupled Receptors (AGPCRs)(1)
- Taste Receptor(1)
- GPR52(1)
Products Related to GPCR/G protein(3732)
- GC84468(-)-Cevimeline hydrochloride hemihydrate
(-)-Cevimeline hydrochloride hemihydrate ((-)-SNI-2011), a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
- GC84469(1S,2S)-2-PCCA hydrochlorideCAS: 1609563-70-3Purity: >99.50%
(1S,2S)-2-PCCA hydrochloride is a less active diastereomer of 2-PCCA.
- GC84488BRL-44408 maleateCAS: 681806-46-2Purity: >99.00%
BRL-44408 maleate is a selective, blood-brain barrier-permeable α 2 A-adrenergic receptor antagonist with a K i value of 8.56 nM against human targets.
- GC84540PD 144418 oxalateCAS: 1794760-28-3Purity: >98.50%
PD 144418 oxalate is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand ( K i values of 0.08 nM and 1377 nM for σ1 and σ2 respectively).
- GC84544β-Melanocyte Stimulating Hormone (MSH), human TFAPurity: >98.00%
β-Melanocyte Stimulating Hormone (MSH), human TFA, a 22-residue peptide, acts as an endogenous melanocortin-4 receptor ( MC4-R ) agonist [1] .
- GC84584Lys-γ3-MSH(human) TFAPurity: >97.00%
Lys-γ3-MSH(human) TFA is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC).
- GC84603SCH-202676 hydrobromideCAS: 265980-25-4Purity: >98.50%
SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors ( GPCRs ) and adenosine receptor ( AR ).
- GC84610Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5)Purity: >99.00%
Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) is an anti-mouse CXCL9/MIG IgG monoclonal antibody.
- GC84611Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5)Purity: >99.50%
Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) is an anti-mouse/rat/human CCL2/MCP-1 IgG monoclonal antibody.
- GC84630(±)-N-MethylcoclaurineCAS: 1472-62-4Purity: >98.00%
(±)-N-Methylcoclaurine is a selective α2-adrenoceptor antagonist [1] .
- GC84634Anti-Mouse CXCR3/CD183 Antibody (CXCR3-173)Purity: >99.00%
Anti-Mouse CXCR3/CD183 Antibody (CXCR3-173) is an anti-mouse CXCR3/CD183 IgG monoclonal antibody.
- GC84655Semaglutide acetateCAS: 1997361-85-9Purity: >99.50%
Semaglutide acetate is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier.
- GC84657Neuropeptide Y (human,rat,mouse) TFAPurity: >99.00%
Neuropeptide Y (human) TFA is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.
- GC84659Anti-TSHR Antibody (K1-70)Purity: >98.00%
Anti-TSHR Antibody (K1-70) is an anti- TSHR monoclonal antibody.
- GC84688Gastrin I (1-14), human TFAPurity: >99.00%
Gastrin I (1-14), human TFA is 1-14 fragment of human gastrin I peptide.
- GC84692BIIE-0246 hydrochloridePurity: >99.00%
BIIE-0246 hydrochloride (AR-H 053591 hydrochloride) is a potent and selective NPY2R ( neuropeptide Y receptor 2) antagonist with an IC 50 value of 15 nM for rat [ 125 I]PYY 3-36.
- GC846935-HT2C agonist-3CAS: 2104810-18-4Purity: >99.50%
5-HT2C agonist-3 ((+)-19) is a selective 5-HT2C agonist ( EC 50: 24 nM, K i: 78 nM).
- GC84698Zinterol hydrochlorideCAS: 38241-28-0Purity: >99.50%
Zinterol hydrochloride (MJ 9184 hydrochloride) is a potent and selective β2-adrenoceptor agonist [1] . Zinterol hydrochloride increases I Ca in a concentration-dependent manner with an EC 50 of 2.2 nM [2] . Zinterol hydrochloride induces ventricular arrhythmias in conscious heart failure rabbits [3] .
- GC84723(+)-SotalolCAS: 30236-32-9Purity: >99.50%
(+)-Sotalol ((S)-Sotalol) is the S-isomer of Sotalol.
- GC84752Calhex 231 hydrochlorideCAS: 2387505-78-2Purity: >99.00%
Calhex 231 hydrochloride is a potent negative allosteric modulator that blocks (IC 50 = 0.39 μM) increases in [ 3 H]inositol phosphates elicited by activating the human wild-type CaSR transiently Ca 2+ -sensing receptor.
- GC84780Glucagon-like peptide 1 (1-37), human TFAPurity: >99.50%
Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC84468 | (-)-Cevimeline hydrochloride hemihydrate | - | - | |
(-)-Cevimeline hydrochloride hemihydrate ((-)-SNI-2011), a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome. | ||||
| GC84469 | (1S,2S)-2-PCCA hydrochloride | 1609563-70-3 | >99.50% | |
(1S,2S)-2-PCCA hydrochloride is a less active diastereomer of 2-PCCA. | ||||
| GC84488 | BRL-44408 maleate | 681806-46-2 | >99.00% | |
BRL-44408 maleate is a selective, blood-brain barrier-permeable α 2 A-adrenergic receptor antagonist with a K i value of 8.56 nM against human targets. | ||||
| GC84540 | PD 144418 oxalate | 1794760-28-3 | >98.50% | |
PD 144418 oxalate is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand ( K i values of 0.08 nM and 1377 nM for σ1 and σ2 respectively). | ||||
| GC84544 | β-Melanocyte Stimulating Hormone (MSH), human TFA | - | >98.00% | |
β-Melanocyte Stimulating Hormone (MSH), human TFA, a 22-residue peptide, acts as an endogenous melanocortin-4 receptor ( MC4-R ) agonist [1] . | ||||
| GC84552 | α-Ionone | 127-41-3 | >94.00% | |
α-Ionone (alpha-Ionone) is an activator of the olfactory receptor OR10A6. | ||||
| GC84584 | Lys-γ3-MSH(human) TFA | - | >97.00% | |
Lys-γ3-MSH(human) TFA is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). | ||||
| GC84603 | SCH-202676 hydrobromide | 265980-25-4 | >98.50% | |
SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors ( GPCRs ) and adenosine receptor ( AR ). | ||||
| GC84610 | Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) | - | >99.00% | |
Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5) is an anti-mouse CXCL9/MIG IgG monoclonal antibody. | ||||
| GC84611 | Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) | - | >99.50% | |
Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) is an anti-mouse/rat/human CCL2/MCP-1 IgG monoclonal antibody. | ||||
| GC84630 | (±)-N-Methylcoclaurine | 1472-62-4 | >98.00% | |
(±)-N-Methylcoclaurine is a selective α2-adrenoceptor antagonist [1] . | ||||
| GC84634 | Anti-Mouse CXCR3/CD183 Antibody (CXCR3-173) | - | >99.00% | |
Anti-Mouse CXCR3/CD183 Antibody (CXCR3-173) is an anti-mouse CXCR3/CD183 IgG monoclonal antibody. | ||||
| GC84655 | Semaglutide acetate | 1997361-85-9 | >99.50% | |
Semaglutide acetate is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. | ||||
| GC84657 | Neuropeptide Y (human,rat,mouse) TFA | - | >99.00% | |
Neuropeptide Y (human) TFA is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity. | ||||
| GC84659 | Anti-TSHR Antibody (K1-70) | - | >98.00% | |
Anti-TSHR Antibody (K1-70) is an anti- TSHR monoclonal antibody. | ||||
| GC84676 | NI-0701 | - | >99.50% | |
NI-0701 is a humanized antibody expressed in CHO cells that targets CCL5/RANTES. | ||||
| GC84688 | Gastrin I (1-14), human TFA | - | >99.00% | |
Gastrin I (1-14), human TFA is 1-14 fragment of human gastrin I peptide. | ||||
| GC84692 | BIIE-0246 hydrochloride | - | >99.00% | |
BIIE-0246 hydrochloride (AR-H 053591 hydrochloride) is a potent and selective NPY2R ( neuropeptide Y receptor 2) antagonist with an IC 50 value of 15 nM for rat [ 125 I]PYY 3-36. | ||||
| GC84693 | 5-HT2C agonist-3 | 2104810-18-4 | >99.50% | |
5-HT2C agonist-3 ((+)-19) is a selective 5-HT2C agonist ( EC 50: 24 nM, K i: 78 nM). | ||||
| GC84698 | Zinterol hydrochloride | 38241-28-0 | >99.50% | |
Zinterol hydrochloride (MJ 9184 hydrochloride) is a potent and selective β2-adrenoceptor agonist [1] . Zinterol hydrochloride increases I Ca in a concentration-dependent manner with an EC 50 of 2.2 nM [2] . Zinterol hydrochloride induces ventricular arrhythmias in conscious heart failure rabbits [3] . | ||||
| GC84723 | (+)-Sotalol | 30236-32-9 | >99.50% | |
(+)-Sotalol ((S)-Sotalol) is the S-isomer of Sotalol. | ||||
| GC84752 | Calhex 231 hydrochloride | 2387505-78-2 | >99.00% | |
Calhex 231 hydrochloride is a potent negative allosteric modulator that blocks (IC 50 = 0.39 μM) increases in [ 3 H]inositol phosphates elicited by activating the human wild-type CaSR transiently Ca 2+ -sensing receptor. | ||||
| GC84768 | (-)-ZK 216348 | - | >99.50% | |
(-)-ZK 216348 is the enantiomer of (+)-ZK 216348. | ||||
| GC84780 | Glucagon-like peptide 1 (1-37), human TFA | - | >99.50% | |
Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor. | ||||