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Acetohydroxamic acid (AHA) (Synonyms: AHA, NSC 5073, NSC 176136, NSC 408425)

Catalog No.GC33978 Copy One-Click Copy Product Info

El Ácido acetohidroxÁmico (AHA) es un inhibidor potente e irreversible de la ureasa bacteriana y vegetal y también se utiliza como tratamiento adyuvante en la infecciÓn urinaria crÓnica.

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Acetohydroxamic acid (AHA) Chemical Structure

Cas No.: 546-88-3

Tamaño Precio Disponibilidad Cantidad
10mM (in 1mL Water)
46,00 $
Disponible
100mg
41,00 $
Disponible
500mg
82,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.



Description of Acetohydroxamic acid (AHA)

Acetohydroxamic acid is a potent and irreversible inhibitor of bacterial and plant urease and also used as adjunctive therapy in chronic urinary infection.Target: UreaseAcetohydroxamic acid selectively inhibits arachidonate 5-lipoxygenase and thus has potential use in the treatment of asthma.

[1]. Sharma M, et al. Biotransformation of Acetamide to Acetohydroxamic Acid at Bench Scale Using Acyl Transferase Activity of Amidase of Geobacillus pallidus BTP-5x MTCC 9225. Indian J Microbiol. 2012 Mar;52(1):76-82.

Chemical Properties of Acetohydroxamic acid (AHA)

Cas No. 546-88-3 SDF
Sinónimos AHA, NSC 5073, NSC 176136, NSC 408425
Canonical SMILES CC(NO)=O
Formula C2H5NO2 M.Wt 75.07
Solubility Water : ≥ 200 mg/mL (2664.18 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Acetohydroxamic acid (AHA)

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 13.3209 mL 66.6045 mL 133.209 mL
5 mM 2.6642 mL 13.3209 mL 26.6418 mL
10 mM 1.3321 mL 6.6605 mL 13.3209 mL
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In vivo Formulation Calculator (Clear solution) of Acetohydroxamic acid (AHA)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for Acetohydroxamic acid (AHA)

Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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