Apararenone (MT-3995) (Synonyms: MT-3995) |
| Catalog No.GC31448 |
La apararenona (MT-3995) (MT-3995) es un nuevo antagonista de los receptores de mineralocorticoides no esteroideos en desarrollo para el tratamiento de las nefropatÍas diabéticas y la esteatohepatitis no alcohÓlica.
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Cas No.: 945966-46-1
Sample solution is provided at 25 µL, 10mM.
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Apararenone (MT-3995) is a novel non-steroidal mineralocorticoid receptor antagonists under development for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.
Recently, a phase II clinical trial has been initiated among patients with non-alcoholic steatohepatitis (NASH) in Japan[1].
[1]. Kolkhof P, et al. 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor antagonists: 60 years of research and development. J Endocrinol. 2017 Jul;234(1):T125-T140.
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