Asperosaponin VI (Synonyms: Akebia Saponin D, ASA VI, Leiyemudanoside A, Tauroside St-G0-1) |
| Catalog No.GC60603 |
A triterpenoid saponin with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 39524-08-8
Sample solution is provided at 25 µL, 10mM.
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Asperosaponin VI, A saponin component from Dipsacus asper wall, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway[1]. Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB[2].
[1]. Niu Y, et al. Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6. [2]. Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
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