- Cat.No. Nombre del producto Información
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GC36231
HIV gag peptide 197-205
El péptido gag del VIH 197-205 es un epítopo restringido por H-2Kd derivado de la porción p24 de la proteína gag del VIH-1, que consta de los aminoácidos 197-205 (AMQMLKETI).
- GC36152 Glucagon-like peptide 1 (1-37), human (TFA)
- GC36151 Glucagon-Like Peptide (GLP) II, human El péptido similar al glucagÓn (GLP) II, humano es un péptido de 33 aminoÁcidos derivado del extremo C del proglucagÓn y producido principalmente por las células L intestinales.
- GC35756 C-Type Natriuretic Peptide (1-53), human El péptido natriurético tipo C (1-53), humano es el fragmento 1-53 del péptido natriurético tipo C.
- GC35723 Competence-Stimulating Peptide-12261 El péptido estimulante de la competencia-12261, un péptido dieciséis, es un fragmento del péptido estimulante de la competencia.
- GC35432 Autocamtide-2-related inhibitory peptide (TFA)
- GC34239 RNAIII-inhibiting peptide(TFA) El péptido inhibidor de ARNIII (TFA) es un potente inhibidor de Staphylococcus aureus, eficaz en enfermedades como celulitis, queratitis, artritis séptica, osteomilitis y mastitis.
- GC33733 Prolactin Releasing Peptide (12-31), human El péptido liberador de prolactina (12-31), humano es un fragmento del péptido liberador de prolactina (PrRP).
- GA24059 3X DYKDDDDK Peptide
- GC62041 IKKγ NBD Inhibitory Peptide TFA
- GC61593 DAPK Substrate Peptide TFA DAPK Substrate Peptide TFA es un sustrato peptÍdico sintético para la proteÍna quinasa asociada a la muerte (DAPK), con una Km de 9 μM.
- GA21285 C-Peptide 2 (rat) C-Peptide 2 (rat) was shown to be effective in augmenting glucose utilization in streptozotocin diabetic rats.
- GC37975 α2β1 Integrin Ligand Peptide α&2#946;1 El péptido ligando de integrina interactúa con el receptor de integrina α2β1 en la membrana celular y media las señales extracelulares en las células.
- GC37783 Thioredoxin reductase peptide TFA El péptido TFA de la tiorredoxina reductasa corresponde a los residuos 53-67 de la tiorredoxina reductasa (TrxR), utilizada en la investigaciÓn de la tiorredoxina reductasa.
- GC37782 Thioredoxin reductase peptide El péptido de la tiorredoxina reductasa corresponde a los residuos 53 a 67 de la tiorredoxina reductasa (TrxR), utilizada en la investigaciÓn de la tiorredoxina reductasa.
- GC37588 Sakamototide substrate peptide TFA El péptido sustrato de sakamototida TFA es un sustrato peptÍdico para miembros de la familia de cinasas AMPK, utilizado en ensayos de actividad de cinasas.
- GC37016 Protein Kinase C Peptide Substrate El sustrato peptÍdico de proteÍna cinasa C se dirige a un compartimento celular especÍfico de una manera dependiente de segundos mensajeros y de proteÍnas adaptadoras especÍficas en respuesta a seÑales extracelulares que activan los receptores acoplados a proteÍna G, los receptores de tirosina cinasa o los receptores acoplados a tirosina cinasa.
- GC36042 Fibronectin CS1 Peptide El segmento de conexiÓn 1 (CS-1) es un dominio de uniÓn celular ubicado en el segmento de conexiÓn de homologÍa tipo III (IIICS) de la fibronectina. El péptido CS1 de fibronectina carece del dominio que contiene Arg-Gly-Asp, inhibe activamente las metÁstasis tumorales en modelos de metÁstasis experimentales y espontÁneas.
- GC35967 EGFRvIII peptide PEPvIII El péptido PEPvIII de EGFRvIII es una mutación específica del tumor que se expresa ampliamente en el glioblastoma multiforme (GBM) y otras neoplasias y su expresión aumenta la tumorigenicidad. El péptido EGFRvIII representa un verdadero objetivo tumoral específico para la inmunoterapia antitumoral.
- GC35594 Calmodulin Binding Peptide 1 El péptido de uniÓn a calmodulina 1 es un péptido de uniÓn a CaM de alta afinidad (pM) derivado de la quinasa de cadena ligera de miosina del mÚsculo liso (péptido MLCK), que inhibe fuertemente la liberaciÓn de Ca2+ inducida por IP3.
- GC35588 Calcitonin Gene Related Peptide (CGRP) II, rat (TFA)
- GC35587 Calcitonin Gene Related Peptide (CGRP) II, rat Péptido relacionado con el gen de la calcitonina (CGRP) II, rata, un activador del receptor CGRP, es un vasodilatador potente y de larga duraciÓn.
- GC35519 Bim BH3, Peptide IV Bim BH3, péptido IV es un péptido de 26 residuos de la proteÍna Bim solo BH3, que pertenece al grupo proapoptÓtico de la familia de proteÍnas Bcl-2.
- GC35085 26Rfa, Hypothalamic Peptide, human 26Rfa, Péptido hipotalÁmico, humano es un neuropéptido hipotalÁmico de la familia de péptidos RFamida con actividad orexigénica.
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GC69976
SV40 T-Ag-derived NLS peptide TFA
SV40 T-Ag-derived NLS péptido TFA es un péptido de señalización de localización nuclear que marca el ADN efectivamente para su transferencia al núcleo celular.
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GC69493
MPG peptides, Pβ
Los péptidos MPG, Pβ son un tipo de péptido anfipático compuesto por tres dominios estructurales.
- GP10158 X-press Tag Peptide
- GP10157 VSV-G Peptide
- GP10156 T7 Tag Peptide
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GP10155
S Tag Peptide
S Tag es el nombre de un oligopéptido derivado de la ribonucleasa A pancreática (RNasa A).
- GP10154 Hexa His tag peptide
- GP10153 V5 Epitope Tag Peptide
- GC61964 HA Peptide TFA El péptido HA (TFA) es un péptido de nueve aminoÁcidos derivado de la hemaglutinina (HA) de la influenza humana.
- GA23583 Tau Peptide (275-305) (Repeat 2 Domain) El péptido tau (275-305) (dominio de repeticiÓn 2) es el fragmento R2 de tau de la enfermedad de Alzheimer, que corresponde a la segunda unidad repetida del dominio de uniÓn a microtÚbulos, que se cree que es fundamental para las propiedades bioquÍmicas de la proteÍna tau completa.
- GA23328 Osteogenic Growth Peptide (10-14) Péptido de crecimiento osteogénico (10-14) (OGP(10-14)), el pentapéptido truncado C-terminal del péptido de crecimiento osteogénico (OGP), retiene la actividad similar a OGP completa.
- GA23113 KALA Amphipathic Peptide El péptido anfipÁtico KALA es un péptido anfifÍlico que forma una estructura helicoidal a pH fisiolÓgico.
- GA23105 Integrin Binding Peptide El péptido de uniÓn a integrina se deriva de la fibronectina.
- GC44536 PACAP-related Peptide (rat) (trifluoroacetate salt) PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin, glucagon, glucagon-like peptide-1, GLP-2, and pituitary adenylate cyclase-activating polypeptide.
- GC44535 PACAP-related Peptide (human) (trifluoroacetate salt) PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin, glucagon, glucagon-like peptide-1, GLP-2, and pituitary adenylate cyclase-activating polypeptide.
- GC44987 TAMRA-Amyloid-β (1-42) Peptide (trifluoroacetate salt) TAMRA-Amyloid-β (1-42) peptide is a fluorescently labeled peptide.
- GC44986 TAMRA-Amyloid-β (1-28) Peptide (human) (trifluoroacetate salt) TAMRA-Amyloid-β (1-28) peptide is a fluorescently labeled peptide.
- GC42505 5-FAM-Amyloid-β (1-28) Peptide (human) (trifluoroacetate salt) 5-FAM-Amyloid-β (1-28) peptide is a fluorescently labeled peptide.
- GC40160 Biotin-Amyloid-β (1-28) Peptide (human) (trifluoroacetate salt) Biotin-amyloid-β (1-28) peptide is a biotinylated peptide.
- GC40130 5-FAM-Amyloid-β (1-42) Peptide (human) (trifluoroacetate salt) 5-FAM-Amyloid-β (1-42) peptide is a fluorescently labeled amyloid-β peptide.
- GC40128 TAMRA-Amyloid-β (1-40) Peptide (human) (trifluoroacetate salt) TAMRA-Amyloid-β (1-40) peptide is a fluorescently labeled peptide.
- GC42937 Biotin-Amyloid-β (1-42) Peptide (trifluoroacetate salt) Biotin-amyloid-β (1-42) peptide is an affinity probe that allows amyloid-β (1-42) (Aβ42) to be detected or immobilized through interaction with the biotin ligand.
- GC42801 Amyloid-β (1-8) Peptide Amyloid-β (1-8) is a wild-type control for the mutation-containing amyloid-β (1-8, A2V) peptide .
- GC15376 Rac1 Inhibitor F56, control peptide Rac1 Inhibitor F56, péptido de control es un péptido que contiene los residuos 45-60 de Rac1.
- GC45465 Glp-Amyloid-β (3-40) Peptide (human) (trifluoroacetate salt)
- GC35335 Amyloid β-peptide (1-40) rat El péptido amiloide β (1-40) de rata es una forma de rata del péptido amiloide β, que se acumula como un depÓsito extracelular insoluble alrededor de las neuronas, dando lugar a las placas seniles asociadas con la enfermedad de Alzheimer ' (AD).
- GC35334 Amyloid β Peptide (42-1)(human) amiloide β El péptido (42-1) (humano) es la forma inactiva del amiloide β Péptido (1-42).
- GC42804 Amyloid-β (40-1) Peptide (human) (trifluoroacetate salt) Amyloid-β (40-1) peptide (Aβ (40-1)) is a peptide that contains the reverse sequence of Aβ (1-40) peptide.
- GC42802 Amyloid-β (1-8, A2V) Peptide Amyloid-β (1-8, A2V) is a truncated form of amyloid-β (Aβ) that contains a valine to alanine substitution at position 2 of the Aβ numbering convention (Aβ A2V), which corresponds to position 673 of the amyloid precursor protein (APP) numbering convention (APP A673V).
- GC42800 Amyloid-β (17-42) Peptide (human) (trifluoroacetate salt) Amyloid-β (Aβ) (17-42) is a 26-residue fragment of the Aβ protein that is formed via post-translational processing of amyloid precursor protein (APP) by α- and γ-secretases.
- GC40129 Biotin-Amyloid-β (1-40) Peptide (trifluoroacetate salt) Biotin-amyloid-β (1-40) (biotin-Aβ40) is an affinity probe that allows amyloid-β (1-40) (Aβ40) to be detected or immobilized through interaction with the biotin ligand.
- GC40126 Amyloid-β Precursor Protein (96-110) Peptide (cyclized) (human) (trifluoroacetate salt) Amyloid-β precursor protein (96-110) peptide (cyclized) is a synthetic peptide consisting of amino acids 96-110 of amyloid precursor peptide (APP) that is cyclized via a bridge between the cysteine residues at positions 3 and 10.
- GC10184 RGD (Arg-Gly-Asp) Peptides Los péptidos RGD (Arg-Gly-Asp) son un tripéptido que desencadena de manera efectiva la adhesiÓn celular, se dirige a ciertas lÍneas celulares y provoca respuestas celulares especÍficas; se une a las integrinas.
- GA24149 Nesfatin-1-Like Peptide (mouse) The insulinotropic peptide encoded by nucleobindin 1 upregulated preproinsulin mRNA expression and insulin secretion.
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GC18339
Amyloid β-Peptide (1-42) human
Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
- GC45050 Thrombin Receptor Agonist Peptide (trifluoroacetate salt) Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor.
- GC39812 LL-37 scrambled peptide acetate El acetato de péptido revuelto LL-37 es una versiÓn revuelta del péptido antimicrobiano de catelicidina LL-37.
- GC50305 Autocamtide-2-related inhibitory peptide, myristoylated El péptido inhibidor relacionado con Autocamtide-2, miristoilado es el péptido inhibidor relacionado con Autocamtide-2 miristoilado.
- GC18366 Prolactin-Releasing Peptide (1-31) (human) El péptido liberador de prolactina (1-31) (humano) es un ligando GPR10 de alta afinidad que provoca la liberación de prolactina.
- GC12034 C-type natriuretic peptide (1-22) (human, rat, swine) El péptido natriurético tipo C (1-22) (humano, rata, cerdo) es un péptido endógeno que se encuentra en el plasma y el líquido cefalorraquídeo.
- GC15230 Eledoisin-Related Peptide El péptido relacionado con la eledoisina es un análogo de la sustancia P que excita las neuronas y desencadena respuestas conductuales.
- GC11385 G-Protein antagonist peptide El péptido antagonista de la proteÍna G es el péptido relacionado con la sustancia P que inhibe la uniÓn de las proteÍnas G a sus receptores.
- GC12743 Calcineurin Autoinhibitory Peptide Selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 mM).
- GC17650 DAPK Substrate Peptide A DAPK1 peptide substrate
- GC61958 T7 Tag Peptide TFA T7 Tag Peptide TFA es una proteÍna etiqueta derivada de los 11 residuos N-terminales de la principal proteÍna de la cÁpside T7, gp 10.
- GC47962 PKCε Inhibitor Scramble Peptide A negative control for PKCε inhibitor peptide
- GC50020 Dynamin inhibitory peptide, myristoylated El péptido inhibidor de DynaMin, miristoilado, es un inhibidor de DynaMin que interfiere con la uniÓn de la anfifisina con la dinamina.
- GC45051 Thrombin Receptor Peptide Ligand (trifluoroacetate salt) Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro).
- GC44984 TAF 10 Peptide TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity.
- GC43838 Histone H3 Trimethyl Lys9 Peptide Histone H3 undergoes many modifications including acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.
- GC30400 Thymus peptide C El péptido C del timo es un fÁrmaco hormonal derivado de las glÁndulas del timo de los terneros jÓvenes, que actÚa como sustituto de las funciones fisiolÓgicas del timo.
- GC17510 Compstatin control peptide El péptido de control de compstatina es un control negativo de compstatina.
- GC10159 PDZ1 Domain inhibitor peptide El péptido inhibidor del dominio PDZ1, un péptido cÍclico, incorpora un conector de cadena lateral de lactama β-Ala y se dirige a los dominios PDZ1 de la proteÍna de densidad postsinÁptica 95 (PSD-95).
- GC15822 Akt/SKG Substrate Peptide Akt/SKG Substrate Peptide es un péptido sintético adecuado como sustrato para Akt/PKB, que no es fosforilado por p70S6K o MAPK1.
- GC12364 SAMS Peptide El péptido SAMS Peptide es un sustrato especÍfico para la proteÍna quinasa activada por AMP (AMPK).
- GA24136 H-Pro-2-chlorotrityl resin (200-400 mesh, 0.80-1.20 mmol/g) Peptides containing a C-terminal Pro can be readily obtained on 2-chlorotrityl resin, as diketopiperazine formation is suppressed by the bulky anchor group.
- GA24121 H-Cys(Trt)-2-chlorotrityl resin (200-400 mesh, 0.50-0.90 mmol/g) Peptides containing C-terminal cysteines can be obtained with practically no racemization by Fmoc-based SPPS using 2-chlorotrityl chloride resin.
- GC13724 JIP-1 (153-163) JIP-1 (153-163) (TI-JIP) es un inhibidor peptídico de c-JNK, basado en los residuos 153-163 de la proteína 1 que interactúa con JNK (JIP-1) (Modificaciones: Phe-11 \u003d C-terminal amida).
- GC10927 CGRP 8-37 (rat) CGRP 8-37 (rata) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) es un antagonista del receptor CGRP altamente selectivo.
- GA21423 ent-[Amyloid β-Protein (20-16)]-β-Ala-D-Lys(ent-[Amyloid β-Protein (16-20)]) This all-D peptide contains two retro-inverso peptide klvff motifs of KLVFF (H-3682) corresponding to amino acids 16 to 20 of amyloid β-protein. The tandem dimer retro-inverso peptide showed about a 100-fold higher binding affinity (Kd = 1.3 . 10?² µM) for amyloid β-protein (1-40) fibrils than KLVFF (Kd = 1.1 ± 0.3 µM). It was also found to be more effective in preventing ordered fibril formation than the parent peptide KLVFF as judged by its increased ability to inhibit thioflavin T binding to β-sheet structures.
- GA20182 (Gln²²)-Amyloid β-Protein (1-40) The Dutch mutation (E22Q) of amyloid β-peptide aggregates more readily than the wild-type peptide and the resulting fibrils show increased neurotoxicity. The mutant peptide E22Q induced apoptosis of cerebral endothelial cells at a concentration of 25 μm, whereas WT Aβ 1-40 and the Italian mutant E22K (H-6698) showed no effect.
- GC43764 GLP-2 (human) (trifluoroacetate salt) Glucagon-like peptide-2 (GLP-2) is an endogenous peptide hormone formed in L cells of the small and large intestine by cleavage of proglucagon in response to nutrient ingestion.
- GC43567 DPC-AJ1951 (trifluoroacetate salt) DPC-AJ1951 is a peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR; EC50 = 0.15 nM in HEK293 cells expressing human PPR).
- GC43130 CALP3 (trifluoroacetate salt) CALP3 is a calcium-like peptide that contains the first eight residues of CALP2, which is a 12-residue peptide that interacts with EF hand motif 4 in human calmodulin to activate it in the absence of calcium.
- GC16243 β-Amyloid (1-42), human TFA El TFA humano del péptido β amiloide (1-42) es un péptido de 42 aminoácidos.
- GA20739 Amyloid β-Protein (1-6) amide Experiments using sub-peptides of Aβ42 revealed that the epitope identified by the antibody A8, as described by Ying and coworkers, lies within the 1-6 region of Aβ. The antibody displays high affinity for soluble Aβ42 oligomers in the molecular weight range of 16.5-25 kDa, and detected target antigen in brain sections from senescence-accelerated SAMP 8 mice. Amidated or acetylated and amidated forms of the sequence were used for example for quantitative structure retention relationships (QSRR) experiments. The latter could allow prediction of reversed-phase high-performance liquid chromatography (HPLC) retention of peptides, as reported by Kaliszan and coworkers.
- GA20727 Amyloid β-Protein (1-39) Small quantities of Aβ37, 38 and 39 can be detected in CSF together with Aβ40, the most abundant Aβ homolog, Aβ42, and N-terminally truncated amyloid peptides. The relative amounts depend on the variant of Alzheimer's disease. The C-terminally truncated amyloid peptides are also found in amyloid plaques.
- GA20720 Amyloid β-Protein (10-35) Amyloid β-protein (10-35), YEVHHQKLVFFAEDVGSNKGAIIGLM, was used as a truncated peptide model for the full-length amyloid β-proteins (1-40) and (1-42) in high-resolution structural studies. In contrast to the full-length amyloid β-proteins, amyloid β-protein (10-35) allowed the controlled and reproducible formation of homogeneous fibrils from aqueous solutions of defined pH, ionic strength and soluble peptide concentration necessary for high-resolution structural studies.
- GA20535 Acetyl-Amyloid β-Protein (1-6) amide Experiments using sub-peptides of Aβ42 revealed that the epitope identified by the antibody A8, as described by Ying and coworkers, lies within the 1-6 region of Aβ. The antibody displays high affinity for soluble Aβ42 oligomers in the molecular weight range of 16.5-25 kDa, and detected target antigen in brain sections from senescence-accelerated SAMP 8 mice. Amidated or acetylated and amidated forms of the sequence were used for example for quantitative structure retention relationships (QSRR) experiments. The latter could allow prediction of reversed-phase high-performance liquid chromatography (HPLC) retention of peptides, as reported by Kaliszan and coworkers.
- GA20533 Acetyl-Amyloid β/A4 Protein Precursor₇₇₀ (96-110) (cyclized) This cyclized peptide which is homologous to the heparin-binding domain of APP, binds strongly to heparin and inhibits binding of ¹²?I-labeled APP to heparin (IC??= 10??M). The peptide blocks the heparan sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.
- GA20526 Acetyl-(Pro¹⁸,Asp²¹)-Amyloid β-Protein (17-21) amide The pentapeptide Ac-LPFFD-NH? (iAβ5p) is an analog of product H-4876 with small chemical modifications which enhance its stability against proteolytic degradation. iAβ5p acts as a β-sheet breaker peptide and crosses the blood-brain barrier at a higher rate than most proteins and peptides known to be selectively taken up by the brain so that it is assumed that the peptide is being specifically transported to the brain. A significant increase in neuronal survival and decrease in brain inflammation associated with the reduction of amyloid plaques in two different transgenic Alzheimer`s disease (AD) models is additionally reported for iAβ5p.
- GA20284 (Pyr³)-Amyloid β-Protein (3-42) (Pyr³)-Amyloid β-Protein (3-42) was found to be the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. Therefore, (Pyr³)-Aβ (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits. Nussbaum et al. studies the Prion-like behaviour and tau-dependent cytotoxicity of the truncated Aβ sequence.
- GA20030 (Arg⁶)-Amyloid β-Protein (1-40) The English (H6R) mutation of β-amyloid peptides accelerates fibrillation without increasing protofibril formation. Ono et al. showed that the English and Tottori mutations alter Abeta assembly at its earliest stages, monomer folding and oligomerization, and produce oligomers that are more toxic to cultured neuronal cells than are wild type oligomers. The exchange of His? by Arg influences the structure of the Cu(II) complex formed by Aβ peptides.
- GA20024 (7-Diethylaminocoumarin-3-yl)carbonyl-Amyloid β-Protein (1-40) Amyloid β-protein (1-40) that is N-terminally modified with the fluorescent dye (7-diethylaminocoumarin-3-yl)carbonyl (DAC or DEAC). This derivative can be utilized to assess the binding properties of amyloid β-protein (1-40) for various membranes since it behaves very similar to the native peptide. In aqueous environments the fluorophore is almost non-fluorescent whereas binding to membranes results in an increase in fluorescence intensity (Λex = 430 nm, Λem = 470 nm). Increases in the GM1 ganglioside and cholesterol content in the lipid bilayers facilitated the binding of this peptide. For phosphatidylcholine and phosphatidylserine no affinity was observed.
- GC43384 DC4 Crosslinker DC4 crosslinker is a mass spectrometry-cleavable crosslinking reagent (18 in length) that contains two intrinsic positive charges, which allow cross-linked peptides to fragment into their component peptides by collision-induced dissociation or in-source decay.
- GC17966 NFAT Inhibitor A peptide inhibitor of NFAT