- Cat.No. Nombre del producto Información
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GC68860
Chitin synthase inhibitor 4
Chitin synthase inhibitor 4 (compuesto 4fh) is an inhibitor of chitin synthase (CHS) with fungicidal effects. Chitin synthase inhibitor 4 is a potential CHS-based agricultural fungicide.
- GC32113 Ac-CoA Synthase Inhibitor1 Ac-CoA Synthase Inhibitor1 es un inhibidor potente y reversible de la acetil-CoA sintetasa 2 (ACSS2) dependiente de acetato con una IC50 de 0,6 μM.
- GC36233 HIV-1 integrase inhibitor 2 El inhibidor 2 de la integrasa del VIH-1 (CX05168) es un inhibidor de la interacciÓn proteÍna-proteÍna basado en quinolina de LEDGF/p75 y la integrasa del VIH.
- GC12871 CDK9 inhibitor
- GC62415 Tuberculosis inhibitor 3 El inhibidor de la tuberculosis 3 (compuesto 2i) muestra una potente actividad anti-TB (MIC < 0,016 μg/mL) contra las cepas de MTB sensibles/resistentes a los medicamentos.
- GC36939 PLpro inhibitor El inhibidor de PLpro es un potente inhibidor de la proteasa similar a la papaÍna (PLpro) con una IC50 de 2,6 μM.
- GC68023 HIV-1 inhibitor-48
- GC65158 HIV-1 inhibitor-8 El inhibidor 8 del VIH-1 es un inhibidor de la transcriptasa inversa no nucleÓsido (NNRTI) del VIH-1 activo por vÍa oral, de baja toxicidad y potente.
- GC68449 CA inhibitor 1
- GC12998 HIV-1 integrase inhibitor
- GC65256 HIV-1 inhibitor-6 El inhibidor 6 del VIH-1 (compuesto 9), un compuesto a base de diheteroarilamida, es un potente inhibidor alternativo del corte y empalme del pre-ARNm del VIH-1.
- GC36235 HIV-1 integrase inhibitor 4 El inhibidor 4 de la integrasa del VIH-1 es un inhibidor de la transferencia de cadena de la integrasa (INST) del VIH-1 con una IC50 de 3,7 nM.
- GC36234 HIV-1 integrase inhibitor 3 El inhibidor 3 de la integrasa del VIH-1 es un inhibidor de la transferencia de cadena de la integrasa (INST) del VIH-1 con una IC50 de 2,7 nM.
- GC36232 HIV-1 inhibitor-3 El inhibidor 3 del VIH-1 es un inhibidor de la infecciÓn por VIH extraÍdo de la patente US2018360927.
- GC47708 MPro Inhibitor 11b MPro Inhibitor 11b es un inhibidor covalente del SARS-CoV-2 3CLpro, con una IC50 de 40 nM.
- GC47707 MPro Inhibitor 11a An inhibitor of SARS-CoV-2 Mpro
- GC37834 Tuberculosis inhibitor 1 El inhibidor de la tuberculosis 1 es un inhibidor del crecimiento de tripanosoma brucei potente y no citotÓxico con una EC50 de 5 nM.
- GC62208 Mpro inhibitor N3 hemihydrate El inhibidor de Mpro N3 hemihidrato es un potente inhibidor de SARS-CoV-2 Mpro con un EC50 de 16,77 μM para SARS-CoV-2.
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GN10190
Cinnamic acid
trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A.
- GC15391 Cercosporamide A potent inhibitor of fungal Pkc1 and mammalian Mnk isoforms
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GC70089
Ulonivirine
Ulonivirine (MK-8507) is a non-nucleoside reverse transcriptase inhibitor with oral activity and high antiviral activity. Ulonivirine can be used for research on HIV-1 infection.
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GC69873
Seconeolitsine
Seconeolitsine es un antibiótico y un inhibidor dirigido a la enzima topoisomerasa I (TopA). También es un nuevo agente antimicrobiano que puede inhibir el crecimiento de S. pneumoniae. Seconeolitsine tiene actividad inhibitoria contra TopA, con un valor b> IC50 de 17 μM. Seconeolitsine se puede utilizar para investigar infecciones por neumococos resistentes a otros antibióticos.
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GC69861
SARS-CoV-2 nsp13-IN-1
SARS-CoV-2 nsp13-IN-1 (compuesto C1) is an effective inhibitor of nsp13 (proteína no estructural 13). SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA+ ATPasa, with an IC50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA- ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research.
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GC69860
SARS-CoV-2-IN-14
SARS-CoV-2-IN-14 (compuesto 6) is an effective inhibitor of SARS-CoV-2, with an IC50 of 0.39 μM. SARS-CoV-2-IN-14 is a chloronitroaniline analog. SARS-CoV-2-IN-14 has higher stability in human plasma and liver S9 enzyme assays than chloronitroaniline, and oral administration can improve bioavailability and half-life.
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GC69770
Protoneogracillin
Protoneogracillin es un glucósido de furanosterol que tiene actividad inhibitoria contra el hongo fitopatógeno P.oryzae (MMDC=94,0 μM) y actividad citotóxica contra las células cancerosas K562 (IC50=6,6 μM).
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GC69547
Nemonoxacin
Nemonoxacin (TG-873870) is an orally effective and potent broad-spectrum antibiotic. Nemonoxacin has good inhibitory activity against various types of Staphylococcus, Streptococcus, Enterobacteriaceae, Neisseria gonorrhoeae and Haemophilus influenzae. Nemonoxacin can be used for the study of bacterial infections and community-acquired pneumonia.
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GC17373
TMC353121
TMC353121 es un inhibidor de la fusión del VSR.
- GC14454 Tipranavir A nonpeptidic HIV protease inhibitor
- GC16887 Tegobuvir A non-nucleoside inhibitor of HCV NS5B
- GC17270 Simeprevir A potent NS3/4A protease inhibitor
- GC15785 Saquinavir mesylate An HIV protease inhibitor
- GC18107 Salinomycin sodium salt A selective cancer stem cell inhibitor
- GC14882 Salinomycin A selective cancer stem cell inhibitor
- GC11059 Rilpivirine A non-nucleoside reverse transcriptase inhibitor
- GC11859 Peramivir An inhibitor of influenza neuraminidase
- GC14780 Oseltamivir acid A neuraminidase inhibitor and antiviral
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GC14084
Nelfinavir Mesylate
Un inhibidor de la proteasa del VIH-1.
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GC18004
MK-5172
Un inhibidor de la proteasa NS3/4A.
- GC12672 Letermovir A selective inhibitor of HCMV replication
- GC17439 Ledipasvir An HCV NS5A inhibitor
- GC16063 Flavopiridol An inhibitor of cyclin-dependent kinases
- GC11840 Ciluprevir (BILN-2061) Inhibitor of HCV NS3 protease
- GC14386 CHIR-090 An antibiotic and LpxC inhibitor
- GC10959 Boceprevir An NS3/4A protease inhibitor
- GC12236 Daclatasvir dihydrochloride An NS5A inhibitor
- GC10794 BMS-626529 An HIV-1 attachment inhibitor
- GC14602 Avibactam A β-lactamase inhibitor
- GC14458 Asunaprevir (BMS-650032) An HCV NS3/4A protease inhibitor
- GC17867 Pyrimethamine A dihydrofolate reductase inhibitor
- GC16629 Rolipram A phosphodiesterase-4 inhibitor
- GC16347 Roflumilast A PDE4 inhibitor
- GC14269 Cobicistat (GS-9350) An inhibitor of CYP3A
- GC17196 Hesperadin A multi-kinase inhibitor
- GC15050 Deuterated Atazanivir-D3-3 HIV-1 protease inhibitor
- GC11772 Deuterated Atazanivir-D3-2 HIV-1 protease inhibitor
- GC15984 Deuterated Atazanivir-D3-1 HIV-1 protease inhibitor
- GC14152 Amprenavir (agenerase) A selective HIV protease inhibitor
- GC16602 Darunavir An HIV-1 protease inhibitor
- GC17303 Ritonavir An HIV protease inhibitor
- GC10240 Atazanavir sulfate (BMS-232632-05) An inhibitor of HIV-1 protease
- GC12945 Atazanavir An inhibitor of HIV-1 protease
- GC15794 Valproic acid sodium salt (Sodium valproate) A class I HDAC inhibitor
- GC10832 VX-222 (VCH-222, Lomibuvir) An HCV polymerase inhibitor
- GC12299 Telaprevir (VX-950) An HCV NS3/4A protease inhibitor
- GC12879 Danoprevir (RG7227) An HCV NS3/4A protease inhibitor
- GC17906 S/GSK1349572 A potent inhibitor of HIV integrase
- GC14996 Elvitegravir (GS-9137) An inhibitor of HIV-1 integrase
- GC13433 AZ 960 A JAK2 inhibitor
- GC15706 Aspirin (Acetylsalicylic acid) A non-selective, irreversible COX inhibitor
- GC16901 PSI-6206 An inactive derivative of a HCV NS5B inhibitor
- GC12257 Panobinostat (LBH589) A pan-HDAC inhibitor
- GC15089 Carfilzomib (PR-171) A proteasome inhibitor
- GC13716 Lopinavir A potent HIV-1 protease inhibitor
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GC14502
AEBSF.HCl
AEBSF.HCl is a broad-spectrum irreversible inhibitor of serine proteases, which can inhibit chymotrypsin, kallikrein, plasmin, thrombin, trypsin and related thrombolytic enzymes.
- GC25867 Rilpivirine Hydrochloride Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
- GC25671 NK01-63 NK01-63 (Coronastat) is a potent inhibitor of the SARS-CoV-2 3CL protease, which is a critical drug target for small molecule COVID-19, given its likely druggability and essentiality in the viral maturation and replication cycle.
- GC25249 CID-1517823 CID-1517823 (ML328) is a potent and selective inhibitor of bacterial AddAB and RecBCD helicase-nucleases, with IC50s of 1.0 and 4.8 μM.
- GC52501 2',3'-Dideoxyadenosine 5'-triphosphate (lithium salt) An inhibitor of reverse transcriptases and DNA polymerases
- GC52315 GK241 An sPLA2 (Type IIA) inhibitor
- GC52272 Jun9-72-2 A SARS-CoV-2 PLpro inhibitor
- GC63790 MERS-CoV-IN-1 MERS-CoV-IN-1 exhibe una excelente actividad inhibitoria contra el coronavirus.
- GC49646 Aurothioglucose (hydrate) A TrxR inhibitor
- GC49265 PKI (14-22) amide (myristoylated) (trifluoroacetate salt) A PKA inhibitor
- GC49144 NAG-thiazoline An OGA inhibitor
- GC49139 CAY10784 A STAT3 inhibitor
- GC62631 PF-07321332 PF-07321332 (PF-07321332) es un inhibidor de la proteasa similar al SARS-CoV3C (3CLPRO) potente y activo por vÍa oral.
- GC62321 AT-527 AT-527 (AT-527), una sal de hemisulfato de AT-511, un profÁrmaco de nucleÓtido de guanosina, es un inhibidor de la replicaciÓn viral del VHC potente y activo por vÍa oral.
- GC48873 2′-O-Methylcytidine &2#8242;-O-metilcitidina es un nucleósido sustituido en 2' como inhibidor de la replicación del VHC.
- GC48652 Olomoucine II A CDK inhibitor
- GC48439 IMP-1700 An inhibitor of bacterial DNA repair
- GC47741 Nalanthalide A fungal metabolite with potassium channel inhibitory and antiviral activities
- GC47693 m-Methoxybenzamide La m-metoxibenzamida (3-MBA), un inhibidor de la ADP-ribosiltransferasa (ADPRT) y PARP, inhibe la divisiÓn celular en Bacillus subtilis, lo que lleva a la filamentaciÓn y, finalmente, a la lisis de las células. La m-metoxibenzamida (3-MBA) mejora el crecimiento de plantas in vitro, la microtuberizaciÓn y la eficiencia de transformaciÓn de la papa azul (Solanum tuberosum L. subsp. andigenum).
- GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities
- GC61276 Silver sulfadiazine La sulfadiazina de plata (AgSD), un antibiÓtico de sulfonamida, ejerce una doble acciÓn inhibitoria sobre el crecimiento bacteriano mediante su fracciÓn sulfa (SD-SDZ) que impide la absorciÓn de folato bacteriano y la subsiguiente sÍntesis de ADN.
- GC61079 Monensin Monensin (inhibidor del transporte de proteínas) es un ionóforo, que puede destruir el aparato de Golgi e inhibir el transporte de proteínas intracelulares.
- GC60840 FGI-106 tetrahydrochloride El tetrahidrocloruro de FGI-106 es un inhibidor potente y de amplio espectro con actividad inhibitoria contra mÚltiples virus.
- GC60667 BSH-IN-1 BSH-IN-1 es un inhibidor potente y covalente de las hidrolasas de sales biliares recombinantes (BSH) bacterianas intestinales con IC50 de 108 nM y 427 nM para B.
- GC39601 Chlormidazole hydrochloride El clorhidrato de clormidazol es un agente antifÚngico y tiene actividad inhibitoria contra muchos hongos y algunos cocos grampositivos.
- GC50377 Brequinar sodium Potent and selective DHODH inhibitor
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GC39172
GRL0617
Un inhibidor de PLpro de SARS-CoV y SARS-CoV-2.