CDK7/12-IN-1 |
Catalog No.GC65434 |
CDK7/12-IN-1 es un inhibidor selectivo de CDK7/12 con IC50 de 3 y 277 nM para CDK7 y CDK 12, respectivamente. La inhibiciÓn de CDK7 y CDK12 es una estrategia eficaz para inhibir el crecimiento tumoral.
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Cas No.: 2654075-94-0
Sample solution is provided at 25 µL, 10mM.
CDK7/12-IN-1 is a selective CDK7/12 inhibitor with IC50s of 3 and 277 nM for CDK7 and CDK 12, respectively. CDK7 and CDK12 inhibition is an effective strategy to inhibit tumour growth[1].
[1]. Edward AINSCOW, et al. 4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino]methyl]piperidin-3-ol compounds and their therapeutic use. WO2021122745A1.
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