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CDK7/12-IN-1

Katalog-Nr.GC65434

CDK7/12-IN-1 ist ein selektiver CDK7/12-Inhibitor mit IC50-Werten von 3 und 277 nM fÜr CDK7 bzw. CDK 12. Die Hemmung von CDK7 und CDK12 ist eine wirksame Strategie zur Hemmung des Tumorwachstums.

Products are for research use only. Not for human use. We do not sell to patients.

CDK7/12-IN-1 Chemische Struktur

Cas No.: 2654075-94-0

Größe Preis Lagerbestand Menge
1mg
468,00 $
Auf Lager
5mg
1.314,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

CDK7/12-IN-1 is a selective CDK7/12 inhibitor with IC50s of 3 and 277 nM for CDK7 and CDK 12, respectively. CDK7 and CDK12 inhibition is an effective strategy to inhibit tumour growth[1].

[1]. Edward AINSCOW, et al. 4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino]methyl]piperidin-3-ol compounds and their therapeutic use. WO2021122745A1.

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