FR-190809 |
| Catalog No.GC31551 |
FR-190809 es un inhibidor de acil-CoA:colesterol O-aciltransferasa (ACAT) potente, no adrenotÓxico, eficaz por vÍa oral, con una IC50 de 45 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 215589-63-2
Sample solution is provided at 25 µL, 10mM.
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FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM[1].
FR-190809 inhibits foam cell formation with an IC50 of 215 nM[1].
[1]. Tanaka A, et al. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 3. Discovery of a novel series of N-alkyl-N-[(fluorophenoxy)benzyl]-N'-arylureas with weak toxicological effects on adrenal glands. J Med Chem. 1998 Oct 22;41(22):4408-20.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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