[pSer2, pSer5, pSer7]-CTD TFA |
Catalog No.GC35021 |
[pSer2, pSer5, pSer7]-CTD (TFA), un sustrato para CDK7 (proteÍna quinasa dependiente de ciclina), es un polipéptido fosforilado en los sitios ser2, ser5 y ser7 del dominio carboxi-terminal (CTD) de la ARN polimerasa II.
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Sample solution is provided at 25 µL, 10mM.
[pSer2, pSer5, pSer7]-CTD (TFA), a substrate for CDK7 (cyclin dependent protein kinase), is a phosphorylated polypeptide at ser2, ser5 and ser7 sites of RNA polymerase II carboxy-terminal domain (CTD)[1].
[1]. Czudnochowski N, et al. Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition. Nat Commun. 2012 May 15;3:842.
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