[pSer2, pSer5, pSer7]-CTD TFA |
| カタログ番号GC35021 |
[pSer2, pSer5, pSer7]-CTD (TFA) は、CDK7 (サイクリン依存性プロテインキナーゼ) の基質であり、RNA ポリメラーゼ II カルボキシ末端ドメイン (CTD) の ser2、ser5、および ser7 部位でリン酸化されたポリペプチドです。
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![[pSer2, pSer5, pSer7]-CTD TFA 化学構造](/media/struct/GC3/GC35021.png "[pSer2, pSer5, pSer7]-CTD TFA 化学構造")
Sample solution is provided at 25 µL, 10mM.
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[pSer2, pSer5, pSer7]-CTD (TFA), a substrate for CDK7 (cyclin dependent protein kinase), is a phosphorylated polypeptide at ser2, ser5 and ser7 sites of RNA polymerase II carboxy-terminal domain (CTD)[1].
[1]. Czudnochowski N, et al. Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition. Nat Commun. 2012 May 15;3:842.
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