CHMFL-KIT-033 |
| Catalog No.GC35685 |
CHMFL-KIT-033 es un inhibidor potente y selectivo del mutante c-KIT T670I para tumores del estroma gastrointestinal (GIST), con una IC50 de 0,045 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2351801-41-5
Sample solution is provided at 25 µL, 10mM.
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CHMFL-KIT-033 is a potent and selective inhibitor of c-KIT T670I mutant for gastrointestinal stromal tumors (GISTs), with an IC50 of 0.045 μM[1]. IC50: 0.045 μM (c-KIT T670I mutant)[1]
[1]. Liu X, et al. Discovery of ( E)- N1-(3-Fluorophenyl)- N3-(3-(2-(pyridin-2-yl)vinyl)-1 H-indazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs). J Med Chem. 2019 May 23;62(10):5006-5024.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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