CHMFL-KIT-033 |
| Catalog No.GC35685 |
CHMFL-KIT-033 est un inhibiteur puissant et sélectif du mutant c-KIT T670I pour les tumeurs stromales gastro-intestinales (GIST), avec une IC50 de 0,045 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2351801-41-5
Sample solution is provided at 25 µL, 10mM.
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CHMFL-KIT-033 is a potent and selective inhibitor of c-KIT T670I mutant for gastrointestinal stromal tumors (GISTs), with an IC50 of 0.045 μM[1]. IC50: 0.045 μM (c-KIT T670I mutant)[1]
[1]. Liu X, et al. Discovery of ( E)- N1-(3-Fluorophenyl)- N3-(3-(2-(pyridin-2-yl)vinyl)-1 H-indazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs). J Med Chem. 2019 May 23;62(10):5006-5024.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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