E3 ligase Ligand 13 |
| Catalog No.GC35927 |
E3 ligase Ligand 13 es un ligando para E3 ubiquitina ligasa. El ligando 13 de la ligasa E3 se puede conectar al ligando de la proteÍna mediante un enlazador para formar PROTAC. Los PROTAC son inductores de la degradaciÓn mediada por ubiquitinaciÓn de proteÍnas promotoras del cÁncer.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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E3 ligase Ligand 13 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 13 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
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