EIPA hydrochloride (Synonyms: L593754 hydrochloride; MH 12-43 hydrochloride) |
| Catalog No.GC35970 |
El clorhidrato de EIPA (L593754) es un inhibidor del canal TRPP3 activo por vÍa oral con una IC50 de 10,5 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1345839-28-2
Sample solution is provided at 25 µL, 10mM.
EIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM[1]. EIPA also inhibits Na+/H+-exchanger (NHE)[2] and macropinocytosis[3]. IC50: 10.5 μM (TRPP3 channel)[1]NHE[2]Macropinocytosis[3]
[1]. Dai XQ, et al. Inhibition of TRPP3 channel by MK-870 and analogs. Mol Pharmacol. 2007 Dec;72(6):1576-85. [2]. Shi H, et al. Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells. Cell Physiol Biochem. 2017;42(6):2418-2429. [3]. Zhu BY, et al. A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis.
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *