IDH1 Inhibitor 2 |
| Catalog No.GC36292 |
El inhibidor 2 de IDH1 (compuesto 13) es un potente inhibidor de IDH1 de tipo salvaje a través de una modificaciÓn covalente directa de His315, con una IC50 de 110 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2244895-42-7
Sample solution is provided at 25 µL, 10mM.
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IDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM[1]. IC50: 110 nM (IDH1)[1].
[1]. Jakob CG, et al. Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. J Med Chem. 2018 Aug 9;61(15):6647-6657.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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