IDH1 Inhibitor 2 |
カタログ番号GC36292 |
IDH1 インヒビター 2 (化合物 13) は、His315 の直接共有結合修飾による強力な野生型 IDH1 インヒビターであり、IC50 は 110 nM です。
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Cas No.: 2244895-42-7
Sample solution is provided at 25 µL, 10mM.
IDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM[1]. IC50: 110 nM (IDH1)[1].
[1]. Jakob CG, et al. Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. J Med Chem. 2018 Aug 9;61(15):6647-6657.
Average Rating: 5
(Based on Reviews and 36 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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