LXRβ agonist-2 |
| Catalog No.GC36499 |
LXR&2#946; El agonista-2 es un agonista del receptor X hepático (LXRβ) altamente potente y β-selectivo con EC50 de 7 nM, muestra una selectividad de 28,5 veces sobre LXRα (EC50 \u003d 200 nM) y se usa en el tratamiento de la aterosclerosis.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1949801-52-8
Sample solution is provided at 25 µL, 10mM.
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LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM, displays 28.5-fold selectivity over LXRα (EC50=200 nM) and used in the treatment of atherosclerosis[1]. EC50: 7 nM (LXRβ), 200 nM (LXRα)[1]
[1]. Koura M,et al. Discovery of a 2-hydroxyacetophenone derivative as an outstanding linker to enhance potency and β-selectivity of liver X receptor agonist. Bioorg Med Chem. 2016 Aug 15;24(16):3436-46.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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