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LSD1-IN-6

Catalog No.GC36485

LSD1-IN-6 (Compuesto 4m) es un inhibidor potente y reversible de la desmetilasa 1 especÍfica de lisina (LSD1), con una IC50 de 123 nM. LSD1-IN-6 aumenta la Lys4 dimetilada de la histona H3, no muestra ningÚn efecto sobre la expresiÓn de LSD1.

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LSD1-IN-6 Chemical Structure

Cas No.: 2035912-43-5

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

LSD1-IN-6 (Compound 4m) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1]. IC50: 123 nM (LSD1)[1]

[1]. Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.

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