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PNZ5

Catalog No.GC36943

PNZ5 es un inhibidor pan-BET potente y basado en isoxazol con alta selectividad y potencia similar al bien establecido (+)-JQ1, con una KD de 5,43 nM para BRD4(1).

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PNZ5 Chemical Structure

Cas No.: 1629277-36-6

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1)[1]. BRD4(1)|5.43 nM (Kd)

[1]. Montenegro RC, et al. BET inhibition as a new strategy for the treatment of gastric cancer. Oncotarget. 2016 Jul 12;7(28):43997-44012.

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Average Rating: 5 ★★★★★ (Based on Reviews and 11 reference(s) in Google Scholar.)

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