PNZ5 |
| カタログ番号GC36943 |
PNZ5 は、確立された (+)-JQ1 と同様の高い選択性と効力を持つ強力なイソオキサゾールベースの汎 BET 阻害剤であり、BRD4 の KD は 5.43 nM です(1)。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1629277-36-6
Sample solution is provided at 25 µL, 10mM.
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PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4(1)[1]. BRD4(1)|5.43 nM (Kd)
[1]. Montenegro RC, et al. BET inhibition as a new strategy for the treatment of gastric cancer. Oncotarget. 2016 Jul 12;7(28):43997-44012.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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