Taccalonolide AJ |
Catalog No.GC37716 |
Taccalonolide AJ es un compuesto de semisÍntesis con actividad estabilizadora de microtÚbulos celulares. Taccalonolide AJ muestra una actividad antiproliferativa de alta potencia contra las células cancerosas, con una IC50 de 4,2 nM para las células HeLa.
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Cas No.: 1349904-82-0
Sample solution is provided at 25 µL, 10mM.
Taccalonolide AJ is a semi-synthesis compound with cellular microtubule stabilizing activity. Taccalonolide AJ exhibits high potency antiproliferative activity against cancer cells, with an IC50 of 4.2 nM for HeLa cells[1]. microtubule[1]
[1]. Li J, et al. Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers. J Am Chem Soc. 2011 Nov 30;133(47):19064-7.
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