Taccalonolide AJ |
| カタログ番号GC37716 |
タッカロノライド AJ は、細胞の微小管安定化活性を持つ半合成化合物です。タッカロノライド AJ は、がん細胞に対して強力な抗増殖活性を示し、HeLa 細胞に対する IC50 は 4.2 nM です。
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Cas No.: 1349904-82-0
Sample solution is provided at 25 µL, 10mM.
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Taccalonolide AJ is a semi-synthesis compound with cellular microtubule stabilizing activity. Taccalonolide AJ exhibits high potency antiproliferative activity against cancer cells, with an IC50 of 4.2 nM for HeLa cells[1]. microtubule[1]
[1]. Li J, et al. Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers. J Am Chem Soc. 2011 Nov 30;133(47):19064-7.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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