Eriocitrin (Synonyms: Eriodictioside, Eriodictyol 7-O-rutinoside) |
Catalog No.GC38181 |
La eriocitrina es un flavonoide aislado del limÓn, que es un fuerte agente antioxidante. La eriocitrina podrÍa inhibir la proliferaciÓn de lÍneas celulares de carcinoma hepatocelular al detener el ciclo celular en la fase S a través de la regulaciÓn positiva de p53, ciclina A, ciclina D3 y CDK6. La eriocitrina desencadena la apoptosis al activar la vÍa de seÑalizaciÓn intrÍnseca involucrada en las mitocondrias.
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Cas No.: 13463-28-0
Sample solution is provided at 25 µL, 10mM.
Eriocitrin is a flavonoid isolated from lemon, which is a strong antioxidant agent. Eriocitrin could inhibit the proliferation of hepatocellular carcinoma cell lines by arresting cell cycle in S phase through up-regulation of p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating mitochondria-involved intrinsic signaling pathway[1].
[1]. Wang Z, et al. Eriocitrin from lemon suppresses the proliferation of human hepatocellular carcinoma cells through inducing apoptosis and arresting cell cycle. Cancer Chemother Pharmacol. 2016 Dec;78(6):1143-1150.
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