Eriocitrin (Synonyms: Eriodictioside, Eriodictyol 7-O-rutinoside) |
| Catalog No.GC38181 |
L'ériocitrine est un flavonoÏde isolé du citron, qui est un puissant agent antioxydant. L'ériocitrine pourrait inhiber la prolifération des lignées cellulaires de carcinome hépatocellulaire en arrêtant le cycle cellulaire en phase S grÂce À la régulation À la hausse de p53, de la cycline A, de la cycline D3 et de CDK6. L'ériocitrine déclenche l'apoptose en activant la voie de signalisation intrinsèque impliquée dans les mitochondries.
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Cas No.: 13463-28-0
Sample solution is provided at 25 µL, 10mM.
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Eriocitrin is a flavonoid isolated from lemon, which is a strong antioxidant agent. Eriocitrin could inhibit the proliferation of hepatocellular carcinoma cell lines by arresting cell cycle in S phase through up-regulation of p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating mitochondria-involved intrinsic signaling pathway[1].
[1]. Wang Z, et al. Eriocitrin from lemon suppresses the proliferation of human hepatocellular carcinoma cells through inducing apoptosis and arresting cell cycle. Cancer Chemother Pharmacol. 2016 Dec;78(6):1143-1150.
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