Gly-Arg-Gly-Asp-Ser |
| Catalog No.GC30223 |
Gly-Arg-Gly-Asp-Ser es un pentapéptido que forma el dominio de uniÓn celular de una glicoproteÍna, la osteopontina.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 96426-21-0
Sample solution is provided at 25 µL, 10mM.
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Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin.
Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC50 of 5 μM[1]. GRGDS-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation[2].
[1]. Bernhagen D, et al. High-Affinity RGD-Knottin Peptide as a New Tool for Rapid Evaluation of the Binding Strength of Unlabeled RGD-Peptides to αvβ3, αvβ5, and α5β1 Integrin Receptors. Anal Chem. 2017 Jun 6;89(11):5991-5997. [2]. Kim GH, et al. Evaluation of Osteoblast-Like Cell Viability and Differentiation on the Gly-Arg-Gly-Asp-Ser Peptide Immobilized Titanium Dioxide Nanotube via Chemical Grafting. J Nanosci Nanotechnol. 2016 Feb;16(2):1396-9.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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