I-SAP (Synonyms: Iodophenyl sulfonyl amino pinane Thromboxane A2, Iodophenyl sulfonyl amino pinane TXA2) |
| Catalog No.GC43910 |
I-SAP is a high affinity TP receptor antagonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 133538-58-6
Sample solution is provided at 25 µL, 10mM.
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I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtained between pH 6.5 and pH 7.4. In washed human platelets, the Kd for I-SAP is 468 pM at pH 7.4 and 490 pM at pH 6.5.
Review for I-SAP
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
Review for I-SAP
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