Laminaran |
| Catalog No.GC39259 |
Laminaran es un β-1-3-glucano y un ligando tÍpico para Dectin-1 de Eisenia Bicyclis, tiene potentes actividades inmunomoduladoras, radioprotectoras y anticancerÍgenas. Laminaran se compone de β (1→3)-glucano con β (1→6)-se ramifica y puede ser catalizado por enzimas como laminarinasa (EC 3.2.1.6) que rompe el β (1→3) bonos. Laminaran es una molécula inmunoestimuladora prometedora para su uso en inmunoterapia contra el cÁncer.
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Cas No.: 9008-22-4
Sample solution is provided at 25 µL, 10mM.
Laminaran is a neutral water-soluble β-1-3-glucan and a typical ligand for Dectin-1 isolated from the brown alga D. dichotoma, has potent immunomodulating, radioprotective, and anticancer activities[1]. Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds[2]. Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy[3].
[1]. Malyarenko OS, et al. Laminaran from brown alga Dictyota dichotoma and its sulfated derivative as radioprotectors and radiosensitizers in melanoma therapy.Carbohydr Polym. 2019 Feb 15;206:539-547. [2]. Laminaran [3]. Song K, et al. Laminarin promotes anti-cancer immunity by the maturation of dendritic cells.Oncotarget. 2017 Jun 13;8(24):38554-38567.
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