Leelamine (hydrochloride) (Synonyms: Dehydroabietylamine) |
Catalog No.GC18496 |
La leelamina (clorhidrato) es una molécula de diterpeno tricíclico que se extrae de la corteza de los pinos.
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Cas No.: 16496-99-4
Sample solution is provided at 25 µL, 10mM.
Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means “play'- It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 uM. Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with an IC50 of 9.5 uM. Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources.
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