Cyclooxygenase
Products for Cyclooxygenase
- Cat.No. Nombre del producto Información
- GC18320 15-keto Prostaglandin E1 15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH.
-
GC40605
15-keto Prostaglandin E2
15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 formed by 15-hydroxy PGDH.
- GC40582 15-keto Prostaglandin F1α 15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH.
-
GC41418
15-keto Prostaglandin F2α
15-keto Prostaglandin F2α (15-keto PGF2α) is the first metabolite of PGF2α.
- GC41935 15-keto Treprostinil (sodium salt) 15-keto Treprostinil is an impurity found in treprostinil, which is a stable analog of prostaglandin I2 with a longer plasma half-life.
- GC41936 15-keto-17-phenyl trinor Prostaglandin F2α Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.
- GC41937 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug.
- GC40974 16(S)-Iloprost Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin.
- GC18778 16,16-dimethyl Prostaglandin A1 16,16-dimethyl PGA1 is a metabolism resistant analog of PGA1.
- GC41942 16,16-dimethyl Prostaglandin A2 16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life.
- GC41159 16,16-dimethyl Prostaglandin D2 16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2.
- GC18777 16,16-dimethyl Prostaglandin E1 16,16-dimethyl PGE1 is a metabolically stable synthetic analog of PGE1.
- GC41943 16,16-dimethyl Prostaglandin E2 p-(p-acetamidobenzamido) phenyl ester The p-(p-acetamidobenzamido) phenyl ester is a crystalline derivative of 16,16-dimethyl PGE2 and a potential prodrug.
- GC18774 16,16-dimethyl Prostaglandin F2α 16,16-dimethyl PGF2α is a metabolically stable analog of PGF2α.
- GC18803 16,16-dimethyl Prostaglandin F2β 16,16-dimethyl PGF2β is a metabolically stable analog of PGF2β.
- GC40762 16-phenoxy Prostaglandin F2α ethyl amide Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
- GC18785 16-phenoxy tetranor Prostaglandin A2 16-phenoxy tetranor PGA2 is a minor metabolite found in human plasma after intravenous administration of sulprostone.
- GC41447 16-phenoxy tetranor Prostaglandin E2 16-phenoxy tetranor PGE2 is the free acid form of sulprostone formed by the hydrolysis of the methylsulfonamide bond.
- GC41946 16-phenoxy tetranor Prostaglandin F2α 16-phenoxy PGF2α is a metabolically stable analog of PGF2α.
- GC41947 16-phenoxy tetranor Prostaglandin F2α cyclopropyl methyl amide The actions of many clinical F-series prostaglandins (PGs), including those used for estrous synchronization and for reduction of intraocular pressure (IOP), are mediated through the PGF2α (FP) receptor.
- GC41948 16-phenoxy tetranor Prostaglandin F2α isopropyl ester Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.
- GC40961 16-phenoxy tetranor Prostaglandin F2α methyl ester Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.
- GC45307 17(R)-Resolvin D3
- GC41209 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils.
- GC41960 17-phenoxy trinor Prostaglandin F2α ethyl amide Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
- GC41963 17-phenyl trinor Prostaglandin A2 17-phenyl trinor PGA2 is a synthetic prostaglandin analog designed for increased half-life and greater potency.
- GC41964 17-phenyl trinor Prostaglandin D2 17-phenyl trinor Prostaglandin D2 (17-phenyl trinor PGD2) is a novel, chemically stable analog of PGD2 wherein the lower side chain is modified by the addition of a phenyl group at C-17 in place of the last 3 ω-chain carbon atoms.
- GC41965 17-phenyl trinor Prostaglandin E2 17-phenyl trinor PGE2 is a synthetic analog of PGE2.
- GC41966 17-phenyl trinor Prostaglandin E2 ethyl amide 17-phenyl trinor PGE2 ethyl amide is derived from 17-phenyl trinor PGE2, a synthetic analog of PGE2 that acts as an agonist of EP1 and EP3 receptors in mice (Ki = 14 and 3.7 nM, respectively) and EP1, EP3, and EP4 in rats (Ki = 25, 4.3, and 54 nM, respectively).
- GC40990 17-phenyl trinor Prostaglandin F2α 17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor.
- GC41967 17-phenyl trinor Prostaglandin F2α amide 17-fenil trinor Prostaglandina F2α la amida es un metabolito N-desetil del bimatoprost.
- GC41969 17-phenyl trinor Prostaglandin F2α cyclopropyl amide 17-phenyl trinor Prostaglandin F2α cyclopropyl amide (17-phenyl trinor PGF2α cyclopropyl amide) is a novel analog of 17-phenyl trinor PGF2α ethyl amide.
- GC41970 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis.
- GC41971 17-phenyl trinor Prostaglandin F2α diethyl amide 17-phenyl trinor Prostaglandin F2α diethyl amide (17-phenyl trinor PGF2α diethyl amide) is an analog of PGF2α in which the C-1 carboxyl group has been modified to an N-diethyl amide.
- GC46458 17-phenyl trinor Prostaglandin F2α dimethyl amide An isomer of 17-phenyl trinor prostaglandin F2α ethyl amide
- GC41972 17-phenyl trinor Prostaglandin F2α isopropyl ester 17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost.
- GC41973 17-phenyl trinor Prostaglandin F2α methyl amide 17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α.
- GC40392 17-phenyl trinor Prostaglandin F2α methyl ester 17-fenil trinor Prostaglandina F2α El éster metÍlico es un profÁrmaco de bimatoprost.
- GC41974 17-phenyl trinor Prostaglandin F2α serinol amide 2-Arachidonyl glycerol (2-AG) exhibits cannabinoid agonist activity at the central cannabinoid (CB1) receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor.
- GC46463 17-phenyl trinor Prostaglandin F2α-d4 An internal standard for the quantification of bimatoprost (free acid)
- GC41292 17-phenyl trinor-13,14-dihydro Prostaglandin A2 17-phenyl trinor-13,14-dihydro Prostaglandin A2 is a synthetic PG analog whose biological activity has not been widely reported.
- GC18739 17-trans Prostaglandin E3 17-trans PGE3 is an isomer of PGE3 which could theoretically result from the COX metabolism of dietary trans-fatty acids.
- GC41420 17-trans Prostaglandin F3α 17-trans PGF3α is a double bond isomer of PGF3α and a potential metabolite of trans dietary fatty acids.
- GC41975 17-trifluoromethylphenyl trinor Prostaglandin F2α A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.
- GC41976 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
- GC41978 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
- GC46465 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F1α An ocular hypotensive agent
- GC46466 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α A prostaglandin F derivative similar to latanoprost free acid
- GC18786 19(R)-hydroxy Prostaglandin A2 Found in human seminal plasma, 19(R)-hydroxy prostaglandin A2 (19(R)-hydroxy PGA2) is presumed to be a non-enzymatic dehydration metabolite of 19(R)-hydroxy PGE2, which is also found in semen.
- GC18816 19(R)-hydroxy Prostaglandin E1 19(R)-hydroxy PGE1 is the major prostaglandin found in the semen of primates, including man.
- GC41473 19(R)-hydroxy Prostaglandin E2 19(R)-hydroxy Prostaglandin E2 (19(R)-hydroxy PGE2) is found in the semen of primates, including man.
- GC41981 19(R)-hydroxy Prostaglandin F1α 19(R)-hydroxy PGF1α is an ω-1 hydroxylase metabolite of PGF1α that has been identified in the semen of humans and marsupials.
- GC40533 19(R)-hydroxy Prostaglandin F2α 19(R)-hydroxy PGF2α is an ω-1 hydroxylase metabolite of PGF2α found in human semen.
- GC18748 1a,1b-dihomo Prostaglandin E1 Prostaglandin E1 (PGE1) is not a major naturally occurring PG, but is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction, and in neonatal cardiology.
- GC41160 1a,1b-dihomo Prostaglandin E2 1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid.
- GC41245 1a,1b-dihomo Prostaglandin F2α 1a,1b-dihomo Prostaglandin F2α (1a,1b-dihomo PGF2α) is the theoretical product of adrenic acid in the COX pathway.
- GC18830 2,3-dinor Prostaglandin E1 Prostaglandin E1 (PGE1) is not a major naturally occurring prostaglandin, but it is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction and in neonatal cardiology.
- GC42065 2,3-dinor Thromboxane B1 Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.
- GC40415 2,3-dinor-11β-Prostaglandin F2α 2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively.
- GC40416 2,3-dinor-8-iso Prostaglandin F2α 8-iso Prostaglandin F2α (8-iso PGF2α; 8-isoprostane) is a prostaglandin-like product of non-specific lipid peroxidation.
- GC41161 20-ethyl Prostaglandin E2 20-ethyl Prostaglandin E2 (20-ethyl PGE2) is an analog of PGE2 in which the ω-chain has been extended by the addition of two methylene carbon atoms.
- GC41246 20-ethyl Prostaglandin F2α 20-ethyl Prostaglandin F2α (20-ethyl PGF2α) is an analog of PGF2α in which the ω-chain has been extended by the addition of two more methylene carbon atoms.
- GC41474 20-hydroxy Prostaglandin E2 20-hydroxy Prostaglandin E2 (20-hydroxy PGE2) is a product of cytochrome P450 metabolism of PGE2.
- GC40534 20-hydroxy Prostaglandin F2α 20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α.
- GC49849 3-Aminosalicylic Acid A salicylic acid derivative
- GC42301 3-methoxy Limaprost Limaprost is an analog of prostaglandin E1 (PGE1) with structural modifications intended to give it a prolonged half-life and greater potency.
- GC18793 3-methoxy Prostaglandin F1α 3-methoxy PGF1α is a novel analog of PGF1α with a methoxy group in the 3-position of the upper side chain.
- GC18527 4'-hydroxy Flurbiprofen A major active metabolite of flurbiprofen
- GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam
- GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone An active metabolite of various polyphenols
- GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid
- GC46682 5-Butyl-4-[2,3-difluoro-4-(phenylmethoxy)phenyl]-6-phenyl-2-pyrimidinamine An mPGES-1 inhibitor
- GC40336 5-cis Carbaprostacyclin 5-cis Carbaprostacyclin is a stable analog of PGI2 and an isomer of carbaprostacyclin.
- GC40976 5-cis Iloprost 5-cis Iloprost is the C-5 cis-isomer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin).
- GC42546 5-hydroxy Diclofenac 5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4.
- GC49119 5-hydroxy Flunixin A metabolite of flunixin
- GC49315 5-hydroxy Indomethacin A metabolite of indomethacin
- GC40284 5-trans Fluprostenol Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.
- GC41590 5-trans Fluprostenol isopropyl ester Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.
- GC41094 5-trans Latanoprost Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.
- GC41228 5-trans Latanoprost (free acid) Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.
- GC41423 5-trans Prostaglandin E2 5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1.
- GC40583 5-trans Prostaglandin F2α 5-trans PGF2α is the more thermodynamically stable C-5 olefin isomer of PGF2α and is a common impurity in commercial lots of PGF2α.
- GC42568 5-trans Prostaglandin F2α (tromethamine salt) 5-trans PGF2α tromethamine salt is a derivative of 5-trans PGF2α with increased water solubility.
- GC40584 5-trans Prostaglandin F2β 5-trans PGF2β is the 9β-hydroxy isomer of 5-trans PGF2α.
- GC40337 5-trans U-44069 5-trans U-44069 is the C-5 double bond isomer of U-44069.
- GC49438 5-trans-17-phenyl trinor Prostaglandin F2α The 5-trans isomer of 17-phenyl trinor PGF2α
- GC40649 5-trans-17-phenyl trinor Prostaglandin F2α ethyl amide 17-phenyl trinor Prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide) is an F-series PG analog which has been approved for use as an ocular hypotensive drug.
- GC40585 6α-Prostaglandin I1 6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions.
- GC40586 6β-Prostaglandin I1 6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions.
- GC40535 6,15-diketo-13,14-dihydro Prostaglandin F1α 6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2.
- GC49183 6-hydroxy Etodolac A metabolite of etodolac
- GC18820 6-keto Prostaglandin E1 6-keto PGE1 is a metabolite isolated after the incubation of PGI2 with rabbit liver microsomes.
- GC18393 6-keto Prostaglandin F1α 6-keto prostaglandin F1α (6-keto PGF1α) is the inactive, non-enzymatic hydrolysis product of PGI2.
- GC18841 6-keto Prostaglandin F1α-d4 6-keto Prostaglandin F1α-d4 (6-keto PGF1α-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions.
- GC46080 7,3',4'-Trihydroxyflavone 7,3',4'-La trihidroxiflavona es un compuesto de aglicÓn flavonoide aislado de las vainas de habas.
- GC49748 7-hydroxy Etodolac An inactive metabolite of etodolac
- GC46741 8(E),10(E),12(Z)-Octadecatrienoic Acid A conjugated PUFA
- GC41138 8-iso Prostaglandin A1 8-iso Prostaglandin A1 (8-iso PGA1) is an isoprostane and a member in a large family of prostanoids of non-cyclooxygenase origin.
- GC40250 9(S)-HODE-d4 MaxSpec® Standard 9(S)-HODE-d4 is intended for use as an internal standard for the quantification of 9(S)-HODE by GC- or LC-mass spectrometry.