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Inicio >> Lipids >> Cyclooxygenase

Cyclooxygenase

Products for  Cyclooxygenase

  1. Cat.No. Nombre del producto Información
  2. GC40338 9-deoxy-9-methylene Prostaglandin E2 9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2. 9-deoxy-9-methylene Prostaglandin E2 Chemical Structure
  3. GC40470 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 Chemical Structure
  4. GC42646 9-keto Fluprostenol 9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency. 9-keto Fluprostenol Chemical Structure
  5. GC42647 9-keto Fluprostenol isopropyl ester Fluprostenol is a well-studied, potent analog of prostaglandin F2α (PGF2α) and acts primarily through the FP receptor. 9-keto Fluprostenol isopropyl ester Chemical Structure
  6. GC46761 9-Oxononanoic Acid An oxidized fatty acid 9-Oxononanoic Acid Chemical Structure
  7. GC42666 AAT-008 AAT-008 es un antagonista del receptor de prostaglandina EP4 potente, selectivo y activo por vÍa oral con Kis de 0,97 y 6,1 nM para EP4 humano recombinante y EP4 de rata recombinante, respectivamente. AAT-008 Chemical Structure
  8. GC42693 Acetaminophen Glucuronide (sodium salt) Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen. Acetaminophen Glucuronide (sodium salt) Chemical Structure
  9. GC42694 Acetaminophen sulfate (potassium salt) Acetaminophen sulfate is a metabolite of acetaminophen. Acetaminophen sulfate (potassium salt) Chemical Structure
  10. GC46781 Acetaminophen-d4 A Certified Reference Material Acetaminophen-d4 Chemical Structure
  11. GC18882 AF3485 AF3485 is a selective 3-aminocarbazole inhibitor of mPGES-1, blocking the synthesis of PGE2 but not PGF2α in A549 cells stimulated with IL-1β (IC50s = 2.9 and >100 µM, respectively). AF3485 Chemical Structure
  12. GC42746 AFP 07 (free acid) Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 (free acid) Chemical Structure
  13. GC42760 AL 6598 Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma. AL 6598 Chemical Structure
  14. GC42761 AL 8810 ethyl amide AL 8810 is an 11β-fluoro analog of prostaglandin F2α (PGF2α) which acts as a potent and selective antagonist at the FP receptor. AL 8810 ethyl amide Chemical Structure
  15. GC42762 AL 8810 methyl ester AL 8810 is an 11β-fluoro analog of prostaglandin F2α (PGF2α) which acts as a potent and selective antagonist at the FP receptor. AL 8810 methyl ester Chemical Structure
  16. GC46862 Apigenin-d5 An internal standard for the quantification of apigenin Apigenin-d5 Chemical Structure
  17. GC46088 ASP7657 An EP4 receptor antagonist ASP7657 Chemical Structure
  18. GC42859 Aspirin-d4 Aspirin-d4 is intended for use as an internal standard for the quantification of aspirin by GC- or LC-MS. Aspirin-d4 Chemical Structure
  19. GC42924 Beraprost (sodium salt) Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. Beraprost (sodium salt) Chemical Structure
  20. GC41106 Bicyclo Prostaglandin E2 Bicyclo prostaglandin E2 (bicyclo PGE2) is a stable breakdown product of PGE2 and 13,14-dihydro-15-keto PGE2. Bicyclo Prostaglandin E2 Chemical Structure
  21. GC42995 Butaprost (free acid) Butaprost is an EP2 selective agonist which has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Butaprost (free acid) Chemical Structure
  22. GC43065 C2 Phytoceramide (t18:0/2:0) C2 Phytoceramide is a bioactive semisynthetic sphingolipid that inhibits formyl peptide-induced oxidant release (IC50 = 0.38 μM) in suspended polymorphonuclear cells. C2 Phytoceramide (t18:0/2:0) Chemical Structure
  23. GC43089 C6 Biotin Glucosylceramide (d18:1/6:0) C6 Biotin glucosylceramide is an affinity probe that allows C6 glucosylceramide to be detected or immobilized through interaction with the biotin ligand. C6 Biotin Glucosylceramide (d18:1/6:0) Chemical Structure
  24. GC40391 Carbaprostacyclin methyl ester Carbaprostacyclin is a stable analog of prostacyclin (prostaglandin I2) which can activate the prostacyclin receptor or PPARδ. Carbaprostacyclin methyl ester Chemical Structure
  25. GC18837 Carbocyclic Thromboxane A2 CTA2 is a stable analog of TXA2. Carbocyclic Thromboxane A2 Chemical Structure
  26. GC18549 CAY10397 Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). CAY10397 Chemical Structure
  27. GC43151 CAY10408 Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. CAY10408 Chemical Structure
  28. GC40384 CAY10410 CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism. CAY10410 Chemical Structure
  29. GC43153 CAY10416 Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer. CAY10416 Chemical Structure
  30. GC43156 CAY10449 Recently, a series of relatively simple compounds were found to be high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. CAY10449 Chemical Structure
  31. GC18811 CAY10471 CAY10471 (TM30089) es un antagonista potente, selectivo y oralmente activo del receptor CRTH2 de prostaglandina D2. CAY10471 Chemical Structure
  32. GC18898 CAY10509 The actions of many clinical prostaglandins, including those used for estrous synchronization and for reduction of intraocular pressure, are mediated through the FP receptor. CAY10509 Chemical Structure
  33. GC43164 CAY10510 The actions of many clinical prostaglandins, including those used for estrous synchronization and for reduction of intraocular pressure, are mediated through the FP receptor. CAY10510 Chemical Structure
  34. GC18856 CAY10526 CAY10526 es un inhibidor especÍfico de la PGE2 sintasa-1 microsomal (mPGES1). CAY10526 inhibe la producciÓn de PGE2 a través de la modulaciÓn selectiva de la expresiÓn de mPGES1 pero no afecta a la COX-2. CAY10526 suprime significativamente el crecimiento tumoral y aumenta la apoptosis en xenoinjertos de melanoma. CAY10526 reduce los niveles de proteÍna BCL-2 y BCL-XL (antiapoptÓticos) y aumenta los niveles de BAX y BAK (proapoptÓticos), asÍ como los niveles de caspasa 3 escindida. CAY10526 inhibe la viabilidad celular (IC50<5 μM) en tres lÍneas celulares de melanoma que expresan mPGES1. CAY10526 Chemical Structure
  35. GC43166 CAY10535 TPα and TPβ are two isoforms of the human TP receptor, the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2). CAY10535 Chemical Structure
  36. GC18814 CAY10580 CAY10580 es un potente y selectivo agonista del receptor de prostaglandina EP4 (Ki = 35 nM). CAY10580 Chemical Structure
  37. GC18688 CAY10589 Microsomal Prostaglandin E2 Synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever and pain. CAY10589 Chemical Structure
  38. GC43181 CAY10597 The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. CAY10597 Chemical Structure
  39. GC18893 CAY10638 Prostaglandins have a short life in vivo because NAD+-dependent 15-hydroxy prostaglandin dehydrogenase (15-PGDH) catalyzes their oxidation to 15-keto metabolites with greatly reduced biological activity. CAY10638 Chemical Structure
  40. GC43191 CAY10684 Prostaglandin E2 activates four E prostanoid (EP) receptors, EP1-4. CAY10684 Chemical Structure
  41. GC18710 CAY10700 Prostaglandin E2 is the major PG synthesized at sites of inflammation and plays an important role in different inflammatory diseases. CAY10700 Chemical Structure
  42. GC49152 Celecoxib Carboxylic Acid An inactive metabolite of celecoxib Celecoxib Carboxylic Acid Chemical Structure
  43. GC43225 Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib. Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide Chemical Structure
  44. GC47070 Celecoxib-d7 An internal standard for the quantification of celecoxib Celecoxib-d7 Chemical Structure
  45. GC43233 CG 4305 Prostacyclin (PGI2) is a cyclooxygenase metabolite with antithrombotic properties found in vascular endothelial cells. CG 4305 Chemical Structure
  46. GC41222 Cicaprost Cicaprost (ZK 96480) es un agonista del receptor de prostaciclina (IP). Cicaprost Chemical Structure
  47. GC43270 Ciprostene (calcium salt) Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene (calcium salt) Chemical Structure
  48. GC45614 Cryogenine An alkaloid with anti-inflammatory activity Cryogenine Chemical Structure
  49. GC47212 Diclofenac amide A prodrug form of diclofenac Diclofenac amide Chemical Structure
  50. GC43447 Diclofenac methyl ester Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac. Diclofenac methyl ester Chemical Structure
  51. GC47213 Diclofenac-d4 An internal standard for the quantification of diclofenac Diclofenac-d4 Chemical Structure
  52. GC52470 Eicosanoids Metabolites MaxSpec® Discovery Mixture A quantitative analytical standard mixture guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Eicosanoids Metabolites MaxSpec® Discovery Mixture Chemical Structure
  53. GC47287 Eltenac Eltenac, un fÁrmaco antiinflamatorio no esteroideo (AINE), es un inhibidor de la COX. Eltenac Chemical Structure
  54. GC43613 ent-Corey PG-Lactone Diol Corey prostaglandin (PG)-lactone diol is a versatile, chiral intermediate used in the preparation of PGs and PG analogs. ent-Corey PG-Lactone Diol Chemical Structure
  55. GC41428 ent-Prostaglandin E2 Enzymatically-derived prostaglandin E2 (PGE2) is an optically pure compound whereas PGE2 derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. ent-Prostaglandin E2 Chemical Structure
  56. GC18794 ent-Prostaglandin F2α Enzymatically-derived Prostaglandin F2α (PGF2α) is an optically pure compound whereas PGF2α derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. ent-Prostaglandin F2α Chemical Structure
  57. GC52516 Erbstatin A tyrosine kinase inhibitor Erbstatin Chemical Structure
  58. GC49156 Etodolac Acyl Glucuronide A phase II metabolite of etodolac Etodolac Acyl Glucuronide Chemical Structure
  59. GC40565 Feprazone Feprazone (DA2370; Prenazone), un anÁlogo de Phenylbutazone, es un agente antiinflamatorio no esteroideo con actividades analgésicas y antipiréticas. Feprazone Chemical Structure
  60. GC48827 Flufenamic Acid-d4 An internal standard for the quantification of flufenamic acid Flufenamic Acid-d4 Chemical Structure
  61. GC49747 Flunixin-d3 An internal standard for the quantification of flunixin Flunixin-d3 Chemical Structure
  62. GC43690 Fluprostenol Lactone Diol Fluprostenol lactone diol is an intermediate used in the preparation of fluprostenol. Fluprostenol Lactone Diol Chemical Structure
  63. GC43691 Fluprostenol methyl amide Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals. Fluprostenol methyl amide Chemical Structure
  64. GC43692 Fluprostenol methyl ester Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals. Fluprostenol methyl ester Chemical Structure
  65. GC43693 Fluprostenol serinol amide 2-arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB1 receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. Fluprostenol serinol amide Chemical Structure
  66. GC47366 Flurbiprofen-d3 An internal standard for the quantification of flurbiprofen Flurbiprofen-d3 Chemical Structure
  67. GC46150 Garcinoic Acid El Ácido garcinoico es el anÁlogo de la vitamina E extraÍdo de las semillas de Garcinia Kola. El Ácido garcinoico muestra un marcado efecto antiproliferativo en las células cancerosas del glioma C6. Garcinoic Acid Chemical Structure
  68. GC43799 GW 848687X Four G protein-coupled receptors, EP1-4, initiate cellular signaling in response to prostaglandin PGE2. GW 848687X Chemical Structure
  69. GC41396 Heneicosapentaenoic Acid Heneicosapentaenoic Acid (HPA) is a 21:5 ω-3 fatty acid present in trace amounts in the green alga B. Heneicosapentaenoic Acid Chemical Structure
  70. GC40814 Heneicosapentaenoic Acid methyl ester

    El Ácido Heneicosapentaenoico (HPA) es un ácido graso presente en cantidades traza en la alga verde Bryopsis pennata Lamouroux y en aceites de pescado.

     Heneicosapentaenoic Acid methyl ester Chemical Structure
  71. GC49130 Hydroxy Celecoxib An inactive metabolite of celecoxib Hydroxy Celecoxib Chemical Structure
  72. GC17816 I-BOP TP specific agonist I-BOP Chemical Structure
  73. GC43910 I-SAP I-SAP is a high affinity TP receptor antagonist. I-SAP Chemical Structure
  74. GC11080 ICI 192,605 ICI 192,605 es un potente antagonista de TXA2R (receptor de tromboxano A2) como prostaglandina de señalización celular. ICI 192,605 Chemical Structure
  75. GC49698 Indomethacin Acyl Glucuronide A metabolite of indomethacin Indomethacin Acyl Glucuronide Chemical Structure
  76. GC41645 Jacaric Acid Jacaric acid is a conjugated polyunsaturated fatty acid first isolated from seeds of Jacaranda plants. Jacaric Acid Chemical Structure
  77. GC47528 Ketorolac (calcium salt) El ketorolaco (RS37619) hemicÁlcico es un fÁrmaco antiinflamatorio no esteroideo (AINE) que actÚa como un inhibidor no selectivo de la COX, con IC50 de 20 nM para COX-1 y 120 nM para COX-2. Ketorolac (calcium salt) Chemical Structure
  78. GC44010 KMN-80 KMN-80, un derivado de PGE1, es un agonista selectivo y potente del receptor EP4 con una CI50 y una Ki de 3 nM y 2,35 nM, respectivamente. KMN-80 Chemical Structure
  79. GC44023 L-902,688 L-902,688 es un agonista del receptor EP4 potente, selectivo y activo por vía oral con una Ki de 0,38 nM y una EC50 de 0,6 nM. L-902,688 Chemical Structure
  80. GC44035 LAS191859 LAS191859 is a potent antagonist of CRTH2/DP2 with IC50 values of 9.58, 14, 15.5, and 7.6 nM for recombinant human, rat, mouse, and guinea pig CRTH2/DP2 receptors, respectively. LAS191859 Chemical Structure
  81. GC47539 Latanoprost (free acid)-d4 Internal standard for the quantification of latanoprost (free acid) Latanoprost (free acid)-d4 Chemical Structure
  82. GC47540 Latanoprost amide A derivative of latanoprost Latanoprost amide Chemical Structure
  83. GC47541 Latanoprost dimethyl amide A derivative of latanoprost Latanoprost dimethyl amide Chemical Structure
  84. GC44037 Latanoprost ethyl amide Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Latanoprost ethyl amide Chemical Structure
  85. GC44038 Latanoprost Lactol Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Latanoprost Lactol Chemical Structure
  86. GC52264 Latanoprost tris(triethylsilyl) ether A precursor in the synthesis of latanoprost Latanoprost tris(triethylsilyl) ether Chemical Structure
  87. GC40239 Limaprost-d3 Limaprost-d3 is intended for use as an internal standard for the quantification of limaprost by GC- or LC-MS. Limaprost-d3 Chemical Structure
  88. GC44092 Lumula There are currently four prostaglandin (PG) derivatives which have been approved for human clinical use for the treatment of glaucoma. Lumula Chemical Structure
  89. GC41178 Lythrine Lythrine is an alkaloid originally isolated from H. Lythrine Chemical Structure
  90. GC47679 Minoxidil-d10 An internal standard for the quantification of minoxidil Minoxidil-d10 Chemical Structure
  91. GC40984 ML-148 ML-148 es un inhibidor potente y selectivo de 15-PGDH con una IC50 de 56 nM. ML-148 Chemical Structure
  92. GC47734 Nabumetone-d3 An internal standard for the quantification of nabumetone Nabumetone-d3 Chemical Structure
  93. GC44433 Nocloprost Nocloprost is a stable prostaglandin E2 analog with gastroprotective and ulcer-healing properties. Nocloprost Chemical Structure
  94. GC49316 O-Desmethyl-N-deschlorobenzoyl Indomethacin A metabolite of indomethacin O-Desmethyl-N-deschlorobenzoyl Indomethacin Chemical Structure
  95. GC49098 Olsalazine-13C6 An internal standard for the quantification of olsalazine Olsalazine-13C6 Chemical Structure
  96. GC49054 Oxaprozin-d5 An internal standard for the quantification of oxaprozin Oxaprozin-d5 Chemical Structure
  97. GC44541 PAF C-18 PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. PAF C-18 Chemical Structure
  98. GC44614 PGDM Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM Chemical Structure
  99. GC49128 Phenylbutazone-d9 An internal standard for the quantification of phenylbutazone Phenylbutazone-d9 Chemical Structure
  100. GC18323 Picotamide La picotamida es un inhibidor combinado de la sintasa y el receptor de tromboxano A2 (TxA2). Picotamide Chemical Structure
  101. GC18707 Pimprinine Pimprinine is an alkaloid originally isolated from Streptomyces that has diverse biological activities, including anticonvulsant, antiplatelet, and antimicrobial properties. Pimprinine Chemical Structure

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