LY3177833 |
| Catalog No.GC19233 |
LY3177833 es un inhibidor de CDC7 y pMCM2 con valores IC50 de 3,3 nM y 290 nM, respectivamente.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1627696-51-8
Sample solution is provided at 25 µL, 10mM.
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LY3177833 is a CDC7 and pMCM2 inhibitor with IC50 values of 3.3 nM and 290 nM, respectively[1].
LY3177833 (Compound example 4; 10.4-31.2 mg/kg; oral gavage; twice a day; for 2 weeks; female athymic Balb/c nude mice with SW620 cells) treatment causes significant tumor regression in a dosedependent manner. Also, no significant tumor growth is observed for 2 weeks after dosing cessation[1].
References:
[1]. DALLY, Robert Dean, et al. CDC7 Inhibitors. 18 September 2014. WO2014143601A1.
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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